Cargando…

Antidepressant Effect of an Orally Administered Dipeptide Mimetic of the Brain-Derived Neurotrophic Factor

Involvement of BDNF in the regulation of neuroplasticity and neurogenesis in the hippocampus, impairment of which underlies the pathophysiology of depression, makes this endogenous protein a promising object for the development of new-generation antidepressants with a neurophysiologically based mech...

Descripción completa

Detalles Bibliográficos
Autores principales:	Povarnina, P. Y., Garibova, T. L., Gudasheva, T. A., Seredenin, S. B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	A.I. Gordeyev 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209401/ https://www.ncbi.nlm.nih.gov/pubmed/30397531

Ejemplares similares

Antidepressant Effect of Dimeric Dipeptide GSB-106, an Original Low-Molecular-Weight Mimetic of BDNF
por: Seredenin, S.B., et al.
Publicado: (2013)

Mimetics of brain-derived neurotrophic factor loops 1 and 4 are active in a model of ischemic stroke in rats
por: Gudasheva, Tatyana A, et al.
Publicado: (2016)

Antidepressant-like Effects of BDNF and NGF Individual Loop Dipeptide Mimetics Depend on the Signal Transmission Patterns Associated with Trk
por: Mezhlumyan, Armen G., et al.
Publicado: (2022)

A Nerve Growth Factor Dipeptide Mimetic Stimulates Neurogenesis and Synaptogenesis in the Hippocampus and Striatum of Adult Rats with Focal Cerebral Ischemia
por: Gudasheva, T. A., et al.
Publicado: (2019)

Original Nerve Growth Factor Mimetic Dipeptide GK-2 Restores Impaired Cognitive Functions in Rat Models of Alzheimer’s Disease
por: Povarnina, P.Yu., et al.
Publicado: (2013)

A Low-Molecular-Weight BDNF Mimetic, Dipeptide GSB-214, Prevents Memory Impairment in Rat Models of Alzheimer’s Disease
por: Povarnina, P. Yu., et al.
Publicado: (2022)

Dimeric dipeptide mimetics of the nerve growth factor Loop 4 and Loop 1 activate TRKA with different patterns of intracellular signal transduction
por: Gudasheva, Tatyana A., et al.
Publicado: (2015)

The Novel Dipeptide Translocator Protein Ligand, Referred to As GD-23, Exerts Anxiolytic and Nootropic Activities
por: Povarnina, P. Yu., et al.
Publicado: (2015)

Low-Molecular Weight BDNF Mimetic, Dimeric Dipeptide GSB-106, Reverses Depressive Symptoms in Mouse Chronic Social Defeat Stress
por: Gudasheva, Tatiana A., et al.
Publicado: (2021)

Novel Technologies for Dipeptide Drugs Design and their Implantation
por: Gudasheva, Tatiana A., et al.
Publicado: (2018)

A Novel Dipeptide NGF Mimetic GK-2 Selectively Activating the PI3K/AKT Signaling Pathway Promotes the Survival of Pancreatic β-Cells in a Rat Model of Diabetes
por: Ostrovskaya, R. U., et al.
Publicado: (2019)

Molecular Mechanism Underlying the Action of Substituted Pro-Gly Dipeptide Noopept
por: Vakhitova, Y. V., et al.
Publicado: (2016)

Low-Molecular-Weight NGF Mimetic Corrects the Cognitive Deficit and Depression-like Behavior in Experimental Diabetes
por: Ostrovskaya, R. U., et al.
Publicado: (2017)

The New Dipeptide TSPO Ligands: Design, Synthesis and Structure–Anxiolytic Activity Relationship †
por: Gudasheva, Tatiana A., et al.
Publicado: (2020)

Dimeric mimetic of BDNF loop 4 promotes survival of serum-deprived cell through TrkB-dependent apoptosis suppression
por: Zainullina, L. F., et al.
Publicado: (2021)

The potential of small molecule brain-derived neurotrophic factor: mimetics to treat inherited retinal degeneration
por: Cerquone Perpetuini, Andrea, et al.
Publicado: (2019)

Participation of the Serotonergic System and Brain-Derived Neurotrophic Factor in the Antidepressant-like Effect of Flavonoids
por: German-Ponciano, León Jesús, et al.
Publicado: (2022)

Antidepressant effect of electroacupuncture regulates signal targeting in the brain and increases brain-derived neurotrophic factor levels
por: Duan, Dong-mei, et al.
Publicado: (2016)

Regulation of proteolytic cleavage of brain-derived neurotrophic factor precursor by antidepressants in human neuroblastoma cells
por: Lin, Pao-Yen
Publicado: (2015)

Plasma Levels of Brain-Derived Neurotrophic Factor and S100B in Relation to Antidepressant Response to Ketamine
por: Jiang, Haitang, et al.
Publicado: (2021)

A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model
por: Daly, Conor, et al.
Publicado: (2017)

Improvement in neurocognitive functions and serum brain-derived neurotrophic factor levels in patients with depression treated with antidepressants and yoga
por: Halappa, Naveen Gowrapura, et al.
Publicado: (2018)

Antidepressant-Like Effects of Acupuncture-Insights From DNA Methylation and Histone Modifications of Brain-Derived Neurotrophic Factor
por: Jiang, Huili, et al.
Publicado: (2018)

Anxiolytic- and Antidepressant-Like Effects of Fish Oil-Enriched Diet in Brain-Derived Neurotrophic Factor Deficient Mice
por: Zemdegs, Juliane, et al.
Publicado: (2018)

Brain-Derived Neurotrophic Factor and Antidepressive Effect of Electroconvulsive Therapy: Systematic Review and Meta-Analyses of the Preclinical and Clinical Literature
por: Polyakova, M., et al.
Publicado: (2015)

Altered Acoustic Startle Reflex, Prepulse Inhibition, and Peripheral Brain-Derived Neurotrophic Factor in Morphine Self-Administered Rats
por: Lee, Bong Hyo, et al.
Publicado: (2016)

Identifying Antidepressant Effects of Brain-Derived Neurotrophic Factor and IDO1 in the Mouse Model Based on RNA-Seq Data
por: Ren, Jing, et al.
Publicado: (2022)

Effects of Antidepressant Medication on Brain-derived Neurotrophic Factor Concentration and Neuroplasticity in Depression: A Review of Preclinical and Clinical Studies
por: Esalatmanesh, Sophia, et al.
Publicado: (2023)

Dipeptide tyrosyl-leucine exhibits antidepressant-like activity in mice
por: Mizushige, Takafumi, et al.
Publicado: (2020)

Brain-derived Neurotrophic Factor in Megakaryocytes
por: Chacón-Fernández, Pedro, et al.
Publicado: (2016)

Brain-derived neurotrophic factor and schizophrenia
por: Gören, Jessica L.
Publicado: (2016)

Brain-derived neurotrophic factor as biomarker
por: Sookaromdee, Pathum, et al.
Publicado: (2020)

Brain-Derived Neurotrophic Factor and Diabetes
por: Rozanska, Olga, et al.
Publicado: (2020)

Chaperone Sigma1R and Antidepressant Effect
por: Voronin, Mikhail V., et al.
Publicado: (2020)

Association study of a brain-derived neurotrophic-factor polymorphism and short-term antidepressant response in major depressive disorders
por: Lin, Eugene, et al.
Publicado: (2008)

Serum Brain-Derived Neurotrophic Factors in Taiwanese Patients with Drug-Naïve First-Episode Major Depressive Disorder: Effects of Antidepressants
por: Chiou, Yu-Jie, et al.
Publicado: (2016)

Korean red ginseng water extract produces antidepressant-like effects through involving monoamines and brain-derived neurotrophic factor in rats
por: Chou, Tzu-wen, et al.
Publicado: (2023)

The impact of antidepressant treatment on brain-derived neurotrophic factor level: An evidence-based approach through systematic review and meta-analysis
por: Arumugam, Vijayakumar, et al.
Publicado: (2017)

Brain-derived neurotrophic factor in primary headaches
por: Fischer, Marlene, et al.
Publicado: (2012)

Brain-Derived Neurotrophic Factor in Chronic Periodontitis
por: Corrêa, Jôice Dias, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_4o44k31js1gab957p7egj9q8d3