Experimental Models of Spinal Cord Injury in Laboratory Rats

Pathologies associated with spinal cord injury are some of the leading diseases in the world. The search for new therapeutic agents and 3D biodegradable materials for the recovery of spinal cord functions is a topical issue. In this review, we have summarized the literature data on the most common e...

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Autores principales: Minakov, A. N., Chernov, A. S., Asutin, D. S., Konovalov, N. A., Telegin, G. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209407/
https://www.ncbi.nlm.nih.gov/pubmed/30397521
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author Minakov, A. N.
Chernov, A. S.
Asutin, D. S.
Konovalov, N. A.
Telegin, G. B.
author_facet Minakov, A. N.
Chernov, A. S.
Asutin, D. S.
Konovalov, N. A.
Telegin, G. B.
author_sort Minakov, A. N.
collection PubMed
description Pathologies associated with spinal cord injury are some of the leading diseases in the world. The search for new therapeutic agents and 3D biodegradable materials for the recovery of spinal cord functions is a topical issue. In this review, we have summarized the literature data on the most common experimental models of spinal cord injury in laboratory rats and analyzed the experience of using 3D biodegradable materials (scaffolds) in experimental studies of spinal trauma. The advantages and disadvantages of the described models are systematically analyzed in this review.
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spelling pubmed-62094072018-11-05 Experimental Models of Spinal Cord Injury in Laboratory Rats Minakov, A. N. Chernov, A. S. Asutin, D. S. Konovalov, N. A. Telegin, G. B. Acta Naturae Research Article Pathologies associated with spinal cord injury are some of the leading diseases in the world. The search for new therapeutic agents and 3D biodegradable materials for the recovery of spinal cord functions is a topical issue. In this review, we have summarized the literature data on the most common experimental models of spinal cord injury in laboratory rats and analyzed the experience of using 3D biodegradable materials (scaffolds) in experimental studies of spinal trauma. The advantages and disadvantages of the described models are systematically analyzed in this review. A.I. Gordeyev 2018 /pmc/articles/PMC6209407/ /pubmed/30397521 Text en Copyright ® 2018 Park-media Ltd. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Minakov, A. N.
Chernov, A. S.
Asutin, D. S.
Konovalov, N. A.
Telegin, G. B.
Experimental Models of Spinal Cord Injury in Laboratory Rats
title Experimental Models of Spinal Cord Injury in Laboratory Rats
title_full Experimental Models of Spinal Cord Injury in Laboratory Rats
title_fullStr Experimental Models of Spinal Cord Injury in Laboratory Rats
title_full_unstemmed Experimental Models of Spinal Cord Injury in Laboratory Rats
title_short Experimental Models of Spinal Cord Injury in Laboratory Rats
title_sort experimental models of spinal cord injury in laboratory rats
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209407/
https://www.ncbi.nlm.nih.gov/pubmed/30397521
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