Wiskott-Aldrich syndrome gene mutations modulate cancer susceptibility in the p53(±) murine model

The Wiskott-Aldrich syndrome protein (WASp) is a key regulator of the actin cytoskeleton in hematopoietic cells and mutated in two severe immunodeficiency diseases with high incidence of cancer. Wiskott-Aldrich syndrome (WAS) is caused by loss-of-function mutations in WASp and most frequently associ...

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Detalles Bibliográficos
Autores principales: Keszei, Marton, Kritikou, Joanna S., Sandfort, Deborah, He, Minghui, Oliveira, Mariana M.S., Wurzer, Hannah, Kuiper, Raoul V., Westerberg, Lisa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209425/
https://www.ncbi.nlm.nih.gov/pubmed/30393584
http://dx.doi.org/10.1080/2162402X.2018.1468954

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