Cargando…

Clostridioides difficile Activates Human Mucosal-Associated Invariant T Cells

Clostridioides difficile infection (CDI) causes severe inflammatory responses at the intestinal mucosa but the immunological mechanisms underlying CDI-related immunopathology are still incompletely characterized. Here we identified for the first time that both, non-toxigenic strains as well as the h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bernal, Isabel, Hofmann, Julia Danielle, Bulitta, Björn, Klawonn, Frank, Michel, Annika-Marisa, Jahn, Dieter, Neumann-Schaal, Meina, Bruder, Dunja, Jänsch, Lothar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209678/ https://www.ncbi.nlm.nih.gov/pubmed/30410474 http://dx.doi.org/10.3389/fmicb.2018.02532

Ejemplares similares

Clostridioides difficile Toxin CDT Induces Cytotoxic Responses in Human Mucosal-Associated Invariant T (MAIT) Cells
por: Marquardt, Isabel, et al.
Publicado: (2021)

Influence of L-lactate and low glucose concentrations on the metabolism and the toxin formation of Clostridioides difficile
por: Hofmann, Julia Danielle, et al.
Publicado: (2021)

Metabolism the Difficile Way: The Key to the Success of the Pathogen Clostridioides difficile
por: Neumann-Schaal, Meina, et al.
Publicado: (2019)

Metabolic Reprogramming of Clostridioides difficile During the Stationary Phase With the Induction of Toxin Production
por: Hofmann, Julia D., et al.
Publicado: (2018)

Thiol Metabolism and Volatile Metabolome of Clostridioides difficile
por: Biwer, Peter, et al.
Publicado: (2022)

Iron Regulation in Clostridioides difficile
por: Berges, Mareike, et al.
Publicado: (2018)

Editorial: The Deadly Secrets of C. difficile—Insights Into Host-Pathogen Interaction
por: Neumann-Schaal, Meina, et al.
Publicado: (2022)

Clostridioides difficile 630Δerm in silico and in vivo – quantitative growth and extensive polysaccharide secretion
por: Dannheim, Henning, et al.
Publicado: (2017)

Translatome analyses by bio-orthogonal non-canonical amino acid labeling reveal that MR1-activated MAIT cells induce an M1 phenotype and antiviral programming in antigen-presenting monocytes
por: Jakob, Josefine, et al.
Publicado: (2023)

Editorial: The Deadly Secrets of C. Difficile—Insights Into Host-Pathogen Interaction, Volume II
por: Neumann-Schaal, Meina, et al.
Publicado: (2022)

A Point Mutation in the Transcriptional Repressor PerR Results in a Constitutive Oxidative Stress Response in Clostridioides difficile 630Δerm
por: Troitzsch, Daniel, et al.
Publicado: (2021)

Characterization of Clostridioides difficile DSM 101085 with A(−)B(−)CDT(+) Phenotype from a Late Recurrent Colonization
por: Riedel, Thomas, et al.
Publicado: (2020)

Protein Kinase Inhibitors CK59 and CID755673 Alter Primary Human NK Cell Effector Functions
por: Scheiter, Maxi, et al.
Publicado: (2013)

Pleiotropic Clostridioides difficile Cyclophilin PpiB Controls Cysteine-Tolerance, Toxin Production, the Central Metabolism and Multiple Stress Responses
por: Ünal, Can Murat, et al.
Publicado: (2019)

Time-resolved amino acid uptake of Clostridium difficile 630Δerm and concomitant fermentation product and toxin formation
por: Neumann-Schaal, Meina, et al.
Publicado: (2015)

Convergent Loss of ABC Transporter Genes From Clostridioides difficile Genomes Is Associated With Impaired Tyrosine Uptake and p-Cresol Production
por: Steglich, Matthias, et al.
Publicado: (2018)

Mucosal Vaccination Strategies against Clostridioides difficile Infection
por: Heuler, Joshua, et al.
Publicado: (2023)

Redefining the Clostridioides difficile σ(B) Regulon: σ(B) Activates Genes Involved in Detoxifying Radicals That Can Result from the Exposure to Antimicrobials and Hydrogen Peroxide
por: Boekhoud, Ilse M., et al.
Publicado: (2020)

Diagnostic Methods of Clostridioides difficile Infection and Clostridioides difficile Ribotypes in Studied Sample
por: Novakova, Elena, et al.
Publicado: (2021)

What’s a Biofilm?—How the Choice of the Biofilm Model Impacts the Protein Inventory of Clostridioides difficile
por: Brauer, Madita, et al.
Publicado: (2021)

Extraintestinal Clostridioides difficile infection
por: Hai, Zhao, et al.
Publicado: (2020)

Pathogenicity and virulence of Clostridioides difficile
por: Buddle, Jessica E., et al.
Publicado: (2023)

BRENDA, the ELIXIR core data resource in 2021: new developments and updates
por: Chang, Antje, et al.
Publicado: (2020)

Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection
por: Ahn, Seung Woo, et al.
Publicado: (2021)

Clostridioides difficile therapeutics: guidelines and beyond
por: Orenstein, Robert, et al.
Publicado: (2019)

Impact of ribotype on Clostridioides difficile diagnostics
por: Rizzardi, Kristina, et al.
Publicado: (2019)

Clostridioides (Clostridium) difficile Pacemaker Infection
por: Berkefeld, Anna, et al.
Publicado: (2020)

Opportunities for Nanomedicine in Clostridioides difficile Infection
por: Wang, Pei-Wen, et al.
Publicado: (2021)

Introduction to the Special Issue on Clostridioides difficile
por: Granata, Guido, et al.
Publicado: (2021)

Epidemiology of Clostridioides difficile in South Africa
por: de Jager, Pieter, et al.
Publicado: (2021)

The repertoire of ABC proteins in Clostridioides difficile
por: Pipatthana, Methinee, et al.
Publicado: (2021)

An Update on Clostridioides difficile Binary Toxin
por: Martínez-Meléndez, Adrián, et al.
Publicado: (2022)

Clostridioides difficile: A diagnostic intervention
por: Alsoubani, Majd, et al.
Publicado: (2022)

Phage therapy for Clostridioides difficile infection
por: Fujimoto, Kosuke, et al.
Publicado: (2022)

Clostridioides difficile, a New “Superbug”
por: Markovska, Rumyana, et al.
Publicado: (2023)

Editorial: Microbial interactions of Clostridioides difficile
por: Goh, Shan, et al.
Publicado: (2023)

PrsA2 (CD630_35000) of Clostridioides difficile Is an Active Parvulin-Type PPIase and a Virulence Modulator
por: Ünal, Can Murat, et al.
Publicado: (2018)

Management of Clostridioides difficile colitis: insights for the gastroenterologist
por: Saha, Srishti, et al.
Publicado: (2019)

Updated Management Guidelines for Clostridioides difficile in Paediatrics
por: Gnocchi, Margherita, et al.
Publicado: (2020)

Clostridioides difficile infection in the Asia-Pacific region
por: Collins, Deirdre A., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0pk5uq4mir89rqc2ma322d5cse