Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient

We report the case of a young patient treated with rituximab-containing chemotherapy who was infected with measles despite previous vaccination. Treatment with vitamin A, ribavirin, and immunoglobulins was started; nevertheless he developed severe pneumonitis and deceased. Broad vaccination coverage...

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Detalles Bibliográficos
Autores principales: Jent, Philipp, Trippel, Mafalda, Frey, Manuel, Pöllinger, Alexander, Berezowska, Sabina, Langer, Rupert, Furrer, Hansjakob, Béguelin, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209686/
https://www.ncbi.nlm.nih.gov/pubmed/30397623
http://dx.doi.org/10.1093/ofid/ofy244
Descripción
Sumario:We report the case of a young patient treated with rituximab-containing chemotherapy who was infected with measles despite previous vaccination. Treatment with vitamin A, ribavirin, and immunoglobulins was started; nevertheless he developed severe pneumonitis and deceased. Broad vaccination coverage is crucial in protecting vulnerable subjects.

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