Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient

We report the case of a young patient treated with rituximab-containing chemotherapy who was infected with measles despite previous vaccination. Treatment with vitamin A, ribavirin, and immunoglobulins was started; nevertheless he developed severe pneumonitis and deceased. Broad vaccination coverage...

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Autores principales: Jent, Philipp, Trippel, Mafalda, Frey, Manuel, Pöllinger, Alexander, Berezowska, Sabina, Langer, Rupert, Furrer, Hansjakob, Béguelin, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209686/
https://www.ncbi.nlm.nih.gov/pubmed/30397623
http://dx.doi.org/10.1093/ofid/ofy244
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author Jent, Philipp
Trippel, Mafalda
Frey, Manuel
Pöllinger, Alexander
Berezowska, Sabina
Langer, Rupert
Furrer, Hansjakob
Béguelin, Charles
author_facet Jent, Philipp
Trippel, Mafalda
Frey, Manuel
Pöllinger, Alexander
Berezowska, Sabina
Langer, Rupert
Furrer, Hansjakob
Béguelin, Charles
author_sort Jent, Philipp
collection PubMed
description We report the case of a young patient treated with rituximab-containing chemotherapy who was infected with measles despite previous vaccination. Treatment with vitamin A, ribavirin, and immunoglobulins was started; nevertheless he developed severe pneumonitis and deceased. Broad vaccination coverage is crucial in protecting vulnerable subjects.
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spelling pubmed-62096862018-11-05 Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient Jent, Philipp Trippel, Mafalda Frey, Manuel Pöllinger, Alexander Berezowska, Sabina Langer, Rupert Furrer, Hansjakob Béguelin, Charles Open Forum Infect Dis Brief Reports We report the case of a young patient treated with rituximab-containing chemotherapy who was infected with measles despite previous vaccination. Treatment with vitamin A, ribavirin, and immunoglobulins was started; nevertheless he developed severe pneumonitis and deceased. Broad vaccination coverage is crucial in protecting vulnerable subjects. Oxford University Press 2018-11-01 /pmc/articles/PMC6209686/ /pubmed/30397623 http://dx.doi.org/10.1093/ofid/ofy244 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Jent, Philipp
Trippel, Mafalda
Frey, Manuel
Pöllinger, Alexander
Berezowska, Sabina
Langer, Rupert
Furrer, Hansjakob
Béguelin, Charles
Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient
title Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient
title_full Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient
title_fullStr Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient
title_full_unstemmed Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient
title_short Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient
title_sort fatal measles virus infection after rituximab-containing chemotherapy in a previously vaccinated patient
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209686/
https://www.ncbi.nlm.nih.gov/pubmed/30397623
http://dx.doi.org/10.1093/ofid/ofy244
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