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HBK-17, a 5-HT(1A) Receptor Ligand With Anxiolytic-Like Activity, Preferentially Activates ß-Arrestin Signaling
Numerous studies have proven that both stimulation and blockade of 5-HT(1A) and the blockade of 5-HT(7) receptors might cause the anxiolytic-like effects. Biased agonists selectively activate specific signaling pathways. Therefore, they might offer novel treatment strategies. In this study, we inves...
Autores principales: | Pytka, Karolina, Głuch-Lutwin, Monika, Żmudzka, Elżbieta, Sałaciak, Kinga, Siwek, Agata, Niemczyk, Katarzyna, Walczak, Maria, Smolik, Magdalena, Olczyk, Adrian, Gałuszka, Adam, Śmieja, Jarosław, Filipek, Barbara, Sapa, Jacek, Kołaczkowski, Marcin, Pańczyk, Katarzyna, Waszkielewicz, Anna, Marona, Henryk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209770/ https://www.ncbi.nlm.nih.gov/pubmed/30410441 http://dx.doi.org/10.3389/fphar.2018.01146 |
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