Cargando…
Tumor–Stroma Cross-Talk in Human Pancreatic Ductal Adenocarcinoma: A Focus on the Effect of the Extracellular Matrix on Tumor Cell Phenotype and Invasive Potential
The extracellular matrix (ECM) in the tumor microenvironment modulates the cancer cell phenotype, especially in pancreatic ductal adenocarcinoma (PDAC), a tumor characterized by an intense desmoplastic reaction. Because the epithelial-to-mesenchymal transition (EMT), a process that provides cancer c...
Autores principales: | Procacci, Patrizia, Moscheni, Claudia, Sartori, Patrizia, Sommariva, Michele, Gagliano, Nicoletta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209911/ https://www.ncbi.nlm.nih.gov/pubmed/30301152 http://dx.doi.org/10.3390/cells7100158 |
Ejemplares similares
-
Stroma Involvement in Pancreatic Ductal Adenocarcinoma: An Overview Focusing on Extracellular Matrix Proteins
por: Liot, Sophie, et al.
Publicado: (2021) -
E-Cadherin in Pancreatic Ductal Adenocarcinoma: A Multifaceted Actor during EMT
por: Sommariva, Michele, et al.
Publicado: (2020) -
Mechanical Cues, E-Cadherin Expression and Cell “Sociality” Are Crucial Crossroads in Determining Pancreatic Ductal Adenocarcinoma Cells Behavior
por: Bianchi, Francesca, et al.
Publicado: (2022) -
The Educational Program of Macrophages toward a Hyperprogressive Disease-Related Phenotype Is Orchestrated by Tumor-Derived Extracellular Vesicles
por: Indino, Serena, et al.
Publicado: (2022) -
In Vitro 3D Cultures to Model the Tumor Microenvironment
por: Fontana, Fabrizio, et al.
Publicado: (2021)