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Tumor–Stroma Cross-Talk in Human Pancreatic Ductal Adenocarcinoma: A Focus on the Effect of the Extracellular Matrix on Tumor Cell Phenotype and Invasive Potential

The extracellular matrix (ECM) in the tumor microenvironment modulates the cancer cell phenotype, especially in pancreatic ductal adenocarcinoma (PDAC), a tumor characterized by an intense desmoplastic reaction. Because the epithelial-to-mesenchymal transition (EMT), a process that provides cancer c...

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Detalles Bibliográficos
Autores principales: Procacci, Patrizia, Moscheni, Claudia, Sartori, Patrizia, Sommariva, Michele, Gagliano, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209911/
https://www.ncbi.nlm.nih.gov/pubmed/30301152
http://dx.doi.org/10.3390/cells7100158

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