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Destruxin B Suppresses Drug-Resistant Colon Tumorigenesis and Stemness Is Associated with the Upregulation of miR-214 and Downregulation of mTOR/β-Catenin Pathway

Background: Drug resistance represents a major challenge for treating patients with colon cancer. Accumulating evidence suggests that Insulin-like growth factor (IGF)-associated signaling promotes colon tumorigenesis and cancer stemness. Therefore, the identification of agents, which can disrupt can...

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Detalles Bibliográficos
Autores principales:	Wu, Szu-Yuan, Huang, Yan-Jiun, Tzeng, Yew-Min, Huang, Chi-Ying F., Hsiao, Michael, Wu, Alexander T.H., Huang, Tse-Hung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209980/ https://www.ncbi.nlm.nih.gov/pubmed/30257507 http://dx.doi.org/10.3390/cancers10100353

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