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Impact of Rehabilitation on Outcomes after TAVI: A Preliminary Study

The benefit of rehabilitation in elderly patients undergoing transcatheter aortic valve implantation (TAVI) for treatment of severe aortic stenosis is unknown. The impact of declining rehabilitation programs on mortality has also not been described. In a longitudinal cohort study of 1056 patients un...

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Autores principales: Butter, Christian, Groß, Jessica, Haase-Fielitz, Anja, Sims, Helen, Deutsch, Cornelia, Bramlage, Peter, Neuss, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210128/
https://www.ncbi.nlm.nih.gov/pubmed/30301135
http://dx.doi.org/10.3390/jcm7100326
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author Butter, Christian
Groß, Jessica
Haase-Fielitz, Anja
Sims, Helen
Deutsch, Cornelia
Bramlage, Peter
Neuss, Michael
author_facet Butter, Christian
Groß, Jessica
Haase-Fielitz, Anja
Sims, Helen
Deutsch, Cornelia
Bramlage, Peter
Neuss, Michael
author_sort Butter, Christian
collection PubMed
description The benefit of rehabilitation in elderly patients undergoing transcatheter aortic valve implantation (TAVI) for treatment of severe aortic stenosis is unknown. The impact of declining rehabilitation programs on mortality has also not been described. In a longitudinal cohort study of 1056 patients undergoing elective TAVI between 2008 and 2016, logistic regression analysis was used to assess the relationship between treatment modality and outcome according to whether or not patients participated in a three-week rehabilitation program after TAVI. Subgroup analyses included patient outcome separated according to cardiac, geriatric, or no rehabilitation. A total of 1017 patients survived until hospital discharge (96.3%) and were offered rehabilitation, 366 patients (36.0%) declined to undergo rehabilitation, with the remaining patients undergoing either cardiac (n = 435; 42.8%) or geriatric rehabilitation (n = 216; 21.2%). Mortality at six months was lower for patients receiving rehabilitation compared with those who had not (adjusted odds ratio (OR): 0.49; 95% confidence interval (confidence interval [CI]: 0.25–0.94; p = 0.032). Sub-analysis showed the benefit of cardiac (adjusted OR: 0.31; 95% CI 0.14–0.71, p = 0.006), but not geriatric rehabilitation (adjusted OR 0.83; 95% CI 0.37–1.85, p = 0.65). A program of rehabilitation after TAVI has the potential to reduce mortality. Future studies should focus on health-orientated behavior and identifying risk factors for declining rehabilitation programs.
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spelling pubmed-62101282018-11-02 Impact of Rehabilitation on Outcomes after TAVI: A Preliminary Study Butter, Christian Groß, Jessica Haase-Fielitz, Anja Sims, Helen Deutsch, Cornelia Bramlage, Peter Neuss, Michael J Clin Med Article The benefit of rehabilitation in elderly patients undergoing transcatheter aortic valve implantation (TAVI) for treatment of severe aortic stenosis is unknown. The impact of declining rehabilitation programs on mortality has also not been described. In a longitudinal cohort study of 1056 patients undergoing elective TAVI between 2008 and 2016, logistic regression analysis was used to assess the relationship between treatment modality and outcome according to whether or not patients participated in a three-week rehabilitation program after TAVI. Subgroup analyses included patient outcome separated according to cardiac, geriatric, or no rehabilitation. A total of 1017 patients survived until hospital discharge (96.3%) and were offered rehabilitation, 366 patients (36.0%) declined to undergo rehabilitation, with the remaining patients undergoing either cardiac (n = 435; 42.8%) or geriatric rehabilitation (n = 216; 21.2%). Mortality at six months was lower for patients receiving rehabilitation compared with those who had not (adjusted odds ratio (OR): 0.49; 95% confidence interval (confidence interval [CI]: 0.25–0.94; p = 0.032). Sub-analysis showed the benefit of cardiac (adjusted OR: 0.31; 95% CI 0.14–0.71, p = 0.006), but not geriatric rehabilitation (adjusted OR 0.83; 95% CI 0.37–1.85, p = 0.65). A program of rehabilitation after TAVI has the potential to reduce mortality. Future studies should focus on health-orientated behavior and identifying risk factors for declining rehabilitation programs. MDPI 2018-10-05 /pmc/articles/PMC6210128/ /pubmed/30301135 http://dx.doi.org/10.3390/jcm7100326 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Butter, Christian
Groß, Jessica
Haase-Fielitz, Anja
Sims, Helen
Deutsch, Cornelia
Bramlage, Peter
Neuss, Michael
Impact of Rehabilitation on Outcomes after TAVI: A Preliminary Study
title Impact of Rehabilitation on Outcomes after TAVI: A Preliminary Study
title_full Impact of Rehabilitation on Outcomes after TAVI: A Preliminary Study
title_fullStr Impact of Rehabilitation on Outcomes after TAVI: A Preliminary Study
title_full_unstemmed Impact of Rehabilitation on Outcomes after TAVI: A Preliminary Study
title_short Impact of Rehabilitation on Outcomes after TAVI: A Preliminary Study
title_sort impact of rehabilitation on outcomes after tavi: a preliminary study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210128/
https://www.ncbi.nlm.nih.gov/pubmed/30301135
http://dx.doi.org/10.3390/jcm7100326
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