Clinical Implications of Hepatitis B Virus RNA and Covalently Closed Circular DNA in Monitoring Patients with Chronic Hepatitis B Today with a Gaze into the Future: The Field Is Unprepared for a Sterilizing Cure

Chronic hepatitis B virus (HBV) infection has long remained a critical global health issue. Covalently closed circular DNA (cccDNA) is a persistent form of the HBV genome that maintains HBV chronicity. Decades of extensive research resulted in the two therapeutic options currently available: nucleot...

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Detalles Bibliográficos
Autores principales: Kostyusheva, Anastasiya, Kostyushev, Dmitry, Brezgin, Sergey, Volchkova, Elena, Chulanov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210151/
https://www.ncbi.nlm.nih.gov/pubmed/30301171
http://dx.doi.org/10.3390/genes9100483

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