Cargando…

A Review of Non-Pharmacological Treatments for Pain Management in Newborn Infants

Pain is a major problem in sick newborn infants, especially for those needing intensive care. Pharmacological pain relief is the most commonly used, but might be ineffective and has side effects, including long-term neurodevelopmental sequelae. The effectiveness and safety of alternative analgesic m...

Descripción completa

Detalles Bibliográficos
Autores principales: Mangat, Avneet K., Oei, Ju-Lee, Chen, Kerry, Quah-Smith, Im, Schmölzer, Georg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210323/
https://www.ncbi.nlm.nih.gov/pubmed/30241352
http://dx.doi.org/10.3390/children5100130
_version_ 1783367087335407616
author Mangat, Avneet K.
Oei, Ju-Lee
Chen, Kerry
Quah-Smith, Im
Schmölzer, Georg M.
author_facet Mangat, Avneet K.
Oei, Ju-Lee
Chen, Kerry
Quah-Smith, Im
Schmölzer, Georg M.
author_sort Mangat, Avneet K.
collection PubMed
description Pain is a major problem in sick newborn infants, especially for those needing intensive care. Pharmacological pain relief is the most commonly used, but might be ineffective and has side effects, including long-term neurodevelopmental sequelae. The effectiveness and safety of alternative analgesic methods are ambiguous. The objective was to review the effectiveness and safety of non-pharmacological methods of pain relief in newborn infants and to identify those that are the most effective. PubMed and Google Scholar were searched using the terms: “infant”, “premature”, “pain”, “acupuncture”, “skin-to-skin contact”, “sucrose”, “massage”, “musical therapy” and ‘breastfeeding’. We included 24 studies assessing different methods of non-pharmacological analgesic techniques. Most resulted in some degree of analgesia but many were ineffective and some were even detrimental. Sucrose, for example, was often ineffective but was more effective than music therapy, massage, breast milk (for extremely premature infants) or non-invasive electrical stimulation acupuncture. There were also conflicting results for acupuncture, skin-to-skin care and musical therapy. Most non-pharmacological methods of analgesia provide a modicum of relief for preterm infants, but none are completely effective and there is no clearly superior method. Study is also required to assess potential long-term consequences of any of these methods.
format Online
Article
Text
id pubmed-6210323
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62103232018-11-05 A Review of Non-Pharmacological Treatments for Pain Management in Newborn Infants Mangat, Avneet K. Oei, Ju-Lee Chen, Kerry Quah-Smith, Im Schmölzer, Georg M. Children (Basel) Review Pain is a major problem in sick newborn infants, especially for those needing intensive care. Pharmacological pain relief is the most commonly used, but might be ineffective and has side effects, including long-term neurodevelopmental sequelae. The effectiveness and safety of alternative analgesic methods are ambiguous. The objective was to review the effectiveness and safety of non-pharmacological methods of pain relief in newborn infants and to identify those that are the most effective. PubMed and Google Scholar were searched using the terms: “infant”, “premature”, “pain”, “acupuncture”, “skin-to-skin contact”, “sucrose”, “massage”, “musical therapy” and ‘breastfeeding’. We included 24 studies assessing different methods of non-pharmacological analgesic techniques. Most resulted in some degree of analgesia but many were ineffective and some were even detrimental. Sucrose, for example, was often ineffective but was more effective than music therapy, massage, breast milk (for extremely premature infants) or non-invasive electrical stimulation acupuncture. There were also conflicting results for acupuncture, skin-to-skin care and musical therapy. Most non-pharmacological methods of analgesia provide a modicum of relief for preterm infants, but none are completely effective and there is no clearly superior method. Study is also required to assess potential long-term consequences of any of these methods. MDPI 2018-09-20 /pmc/articles/PMC6210323/ /pubmed/30241352 http://dx.doi.org/10.3390/children5100130 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mangat, Avneet K.
Oei, Ju-Lee
Chen, Kerry
Quah-Smith, Im
Schmölzer, Georg M.
A Review of Non-Pharmacological Treatments for Pain Management in Newborn Infants
title A Review of Non-Pharmacological Treatments for Pain Management in Newborn Infants
title_full A Review of Non-Pharmacological Treatments for Pain Management in Newborn Infants
title_fullStr A Review of Non-Pharmacological Treatments for Pain Management in Newborn Infants
title_full_unstemmed A Review of Non-Pharmacological Treatments for Pain Management in Newborn Infants
title_short A Review of Non-Pharmacological Treatments for Pain Management in Newborn Infants
title_sort review of non-pharmacological treatments for pain management in newborn infants
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210323/
https://www.ncbi.nlm.nih.gov/pubmed/30241352
http://dx.doi.org/10.3390/children5100130
work_keys_str_mv AT mangatavneetk areviewofnonpharmacologicaltreatmentsforpainmanagementinnewborninfants
AT oeijulee areviewofnonpharmacologicaltreatmentsforpainmanagementinnewborninfants
AT chenkerry areviewofnonpharmacologicaltreatmentsforpainmanagementinnewborninfants
AT quahsmithim areviewofnonpharmacologicaltreatmentsforpainmanagementinnewborninfants
AT schmolzergeorgm areviewofnonpharmacologicaltreatmentsforpainmanagementinnewborninfants
AT mangatavneetk reviewofnonpharmacologicaltreatmentsforpainmanagementinnewborninfants
AT oeijulee reviewofnonpharmacologicaltreatmentsforpainmanagementinnewborninfants
AT chenkerry reviewofnonpharmacologicaltreatmentsforpainmanagementinnewborninfants
AT quahsmithim reviewofnonpharmacologicaltreatmentsforpainmanagementinnewborninfants
AT schmolzergeorgm reviewofnonpharmacologicaltreatmentsforpainmanagementinnewborninfants