Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific

Across 8101 individuals in 46 villages, the proportion of Plasmodium spp. multiple clone infections (0%–53.8%) did not reflect prevalence by quantitative polymerase chain reaction (qPCR; 1.9%–38.4%), except for P. vivax in Solomon Islands (P < .001). Thus this parameter was not informative to ide...

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Autores principales: Koepfli, Cristian, Waltmann, Andreea, Ome-Kaius, Maria, Robinson, Leanne J, Mueller, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210381/
https://www.ncbi.nlm.nih.gov/pubmed/30397622
http://dx.doi.org/10.1093/ofid/ofy240
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author Koepfli, Cristian
Waltmann, Andreea
Ome-Kaius, Maria
Robinson, Leanne J
Mueller, Ivo
author_facet Koepfli, Cristian
Waltmann, Andreea
Ome-Kaius, Maria
Robinson, Leanne J
Mueller, Ivo
author_sort Koepfli, Cristian
collection PubMed
description Across 8101 individuals in 46 villages, the proportion of Plasmodium spp. multiple clone infections (0%–53.8%) did not reflect prevalence by quantitative polymerase chain reaction (qPCR; 1.9%–38.4%), except for P. vivax in Solomon Islands (P < .001). Thus this parameter was not informative to identify transmission foci. In contrast, prevalence by microscopy and qPCR correlated well.
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spelling pubmed-62103812018-11-05 Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific Koepfli, Cristian Waltmann, Andreea Ome-Kaius, Maria Robinson, Leanne J Mueller, Ivo Open Forum Infect Dis Brief Reports Across 8101 individuals in 46 villages, the proportion of Plasmodium spp. multiple clone infections (0%–53.8%) did not reflect prevalence by quantitative polymerase chain reaction (qPCR; 1.9%–38.4%), except for P. vivax in Solomon Islands (P < .001). Thus this parameter was not informative to identify transmission foci. In contrast, prevalence by microscopy and qPCR correlated well. Oxford University Press 2018-09-21 /pmc/articles/PMC6210381/ /pubmed/30397622 http://dx.doi.org/10.1093/ofid/ofy240 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Koepfli, Cristian
Waltmann, Andreea
Ome-Kaius, Maria
Robinson, Leanne J
Mueller, Ivo
Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific
title Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific
title_full Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific
title_fullStr Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific
title_full_unstemmed Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific
title_short Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific
title_sort multiplicity of infection is a poor predictor of village-level plasmodium vivax and p. falciparum population prevalence in the southwest pacific
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210381/
https://www.ncbi.nlm.nih.gov/pubmed/30397622
http://dx.doi.org/10.1093/ofid/ofy240
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