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Vitamin D Supplementation and Nordic Walking Training Decreases Serum Homocysteine and Ferritin in Elderly Women

The aim of the study was to verify if coupling 12 weeks of vitamin D supplementation and Nordic walking training favoured lowering the homocysteine (Hcy) level. Ninety-four elderly women were divided into three groups: Nordic walking (NW), supplemented (SG) and control (CG). The NW and SG groups rec...

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Autores principales: Walentukiewicz, Anna, Lysak-Radomska, Anna, Jaworska, Joanna, Prusik, Krzysztof, Prusik, Katarzyna, Kortas, Jakub Antoni, Lipiński, Marcin, Babinska, Anna, Antosiewicz, Jedrzej, Ziemann, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210625/
https://www.ncbi.nlm.nih.gov/pubmed/30241318
http://dx.doi.org/10.3390/ijerph15102064
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author Walentukiewicz, Anna
Lysak-Radomska, Anna
Jaworska, Joanna
Prusik, Krzysztof
Prusik, Katarzyna
Kortas, Jakub Antoni
Lipiński, Marcin
Babinska, Anna
Antosiewicz, Jedrzej
Ziemann, Ewa
author_facet Walentukiewicz, Anna
Lysak-Radomska, Anna
Jaworska, Joanna
Prusik, Krzysztof
Prusik, Katarzyna
Kortas, Jakub Antoni
Lipiński, Marcin
Babinska, Anna
Antosiewicz, Jedrzej
Ziemann, Ewa
author_sort Walentukiewicz, Anna
collection PubMed
description The aim of the study was to verify if coupling 12 weeks of vitamin D supplementation and Nordic walking training favoured lowering the homocysteine (Hcy) level. Ninety-four elderly women were divided into three groups: Nordic walking (NW), supplemented (SG) and control (CG). The NW and SG groups received a weekly dose of 28,000 IU of vitamin D3. A blood analysis was performed at baseline, 1h after the first training session and at the end of the experiment. The amino acid profile (methionine and cysteine) and homocysteine concentration were determined. Additionally, the concentration of myokine was assessed. The first session of NW training reduced serum homocysteine, particularly among women with baseline homocysteine above 10 µmol·L(−1): 12.37 ± 2.75 vs. 10.95 ± 3.94 µmol·L(−1) (p = 0.05). These changes were accompanied by shifts in the cysteine (p = 0.09) and methionine (p = 0.01) concentration, regardless of the Hcy concentration. Twelve weeks of training significantly decreased the homocysteine (9.91 ± 2.78, vs. 8.90 ± 3.14 µmol·L(−1), p = 0.05) and ferritin (94.23 ± 62.49 vs. 73.15 ± 47.04 ng·mL(−1), p = 0.05) concentrations in whole NW group. Also, in the NW group, ferritin correlated with the glucose level (r = 0.51, p = 0.00). No changes in the myokine levels were observed after the intervention. Only the brain-derived neurotrophic factor dropped in the NW (42.74 ± 19.92 vs. 31.93 ± 15.91 ng·mL(−1), p = 0.01) and SG (37.75 ± 8.08 vs. 16.94 ± 12.78 ng·mL(−1), p = 0.00) groups. This study presents a parallel decrease of homocysteine and ferritin in response to regular training supported by vitamin D supplementation.
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spelling pubmed-62106252018-11-02 Vitamin D Supplementation and Nordic Walking Training Decreases Serum Homocysteine and Ferritin in Elderly Women Walentukiewicz, Anna Lysak-Radomska, Anna Jaworska, Joanna Prusik, Krzysztof Prusik, Katarzyna Kortas, Jakub Antoni Lipiński, Marcin Babinska, Anna Antosiewicz, Jedrzej Ziemann, Ewa Int J Environ Res Public Health Article The aim of the study was to verify if coupling 12 weeks of vitamin D supplementation and Nordic walking training favoured lowering the homocysteine (Hcy) level. Ninety-four elderly women were divided into three groups: Nordic walking (NW), supplemented (SG) and control (CG). The NW and SG groups received a weekly dose of 28,000 IU of vitamin D3. A blood analysis was performed at baseline, 1h after the first training session and at the end of the experiment. The amino acid profile (methionine and cysteine) and homocysteine concentration were determined. Additionally, the concentration of myokine was assessed. The first session of NW training reduced serum homocysteine, particularly among women with baseline homocysteine above 10 µmol·L(−1): 12.37 ± 2.75 vs. 10.95 ± 3.94 µmol·L(−1) (p = 0.05). These changes were accompanied by shifts in the cysteine (p = 0.09) and methionine (p = 0.01) concentration, regardless of the Hcy concentration. Twelve weeks of training significantly decreased the homocysteine (9.91 ± 2.78, vs. 8.90 ± 3.14 µmol·L(−1), p = 0.05) and ferritin (94.23 ± 62.49 vs. 73.15 ± 47.04 ng·mL(−1), p = 0.05) concentrations in whole NW group. Also, in the NW group, ferritin correlated with the glucose level (r = 0.51, p = 0.00). No changes in the myokine levels were observed after the intervention. Only the brain-derived neurotrophic factor dropped in the NW (42.74 ± 19.92 vs. 31.93 ± 15.91 ng·mL(−1), p = 0.01) and SG (37.75 ± 8.08 vs. 16.94 ± 12.78 ng·mL(−1), p = 0.00) groups. This study presents a parallel decrease of homocysteine and ferritin in response to regular training supported by vitamin D supplementation. MDPI 2018-09-20 2018-10 /pmc/articles/PMC6210625/ /pubmed/30241318 http://dx.doi.org/10.3390/ijerph15102064 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Walentukiewicz, Anna
Lysak-Radomska, Anna
Jaworska, Joanna
Prusik, Krzysztof
Prusik, Katarzyna
Kortas, Jakub Antoni
Lipiński, Marcin
Babinska, Anna
Antosiewicz, Jedrzej
Ziemann, Ewa
Vitamin D Supplementation and Nordic Walking Training Decreases Serum Homocysteine and Ferritin in Elderly Women
title Vitamin D Supplementation and Nordic Walking Training Decreases Serum Homocysteine and Ferritin in Elderly Women
title_full Vitamin D Supplementation and Nordic Walking Training Decreases Serum Homocysteine and Ferritin in Elderly Women
title_fullStr Vitamin D Supplementation and Nordic Walking Training Decreases Serum Homocysteine and Ferritin in Elderly Women
title_full_unstemmed Vitamin D Supplementation and Nordic Walking Training Decreases Serum Homocysteine and Ferritin in Elderly Women
title_short Vitamin D Supplementation and Nordic Walking Training Decreases Serum Homocysteine and Ferritin in Elderly Women
title_sort vitamin d supplementation and nordic walking training decreases serum homocysteine and ferritin in elderly women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210625/
https://www.ncbi.nlm.nih.gov/pubmed/30241318
http://dx.doi.org/10.3390/ijerph15102064
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