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A Novel Role for the Interleukin-1 Receptor Axis in Resistance to Anti-EGFR Therapy
Cetuximab (CTX) is a monoclonal antibody targeting the epidermal growth factor receptor (EGFR), commonly used to treat patients with metastatic colorectal cancer (mCRC). Unfortunately, objective remissions occur only in a minority of patients and are of short duration, with a population of cells sur...
Autores principales: | Gelfo, Valerio, Mazzeschi, Martina, Grilli, Giada, Lindzen, Moshit, Santi, Spartaco, D’Uva, Gabriele, Győrffy, Balázs, Ardizzoni, Andrea, Yarden, Yosef, Lauriola, Mattia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210663/ https://www.ncbi.nlm.nih.gov/pubmed/30261609 http://dx.doi.org/10.3390/cancers10100355 |
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