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Oxidation of Methionine 77 in Calmodulin Alters Mouse Growth and Behavior

Methionine 77 in calmodulin can be stereospecifically oxidized to methionine sulfoxide by mammalian methionine sulfoxide reductase A. Whether this has in vivo significance is unknown. We therefore created a mutant mouse in which wild type calmodulin-1 was replaced by a calmodulin containing a mimic...

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Detalles Bibliográficos
Autores principales: Marimoutou, Méry, Springer, Danielle A., Liu, Chengyu, Kim, Geumsoo, Levine, Rodney L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210676/
https://www.ncbi.nlm.nih.gov/pubmed/30322141
http://dx.doi.org/10.3390/antiox7100140