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Drosophila HUWE1 Ubiquitin Ligase Regulates Endoreplication and Antagonizes JNK Signaling During Salivary Gland Development

The HECT-type ubiquitin ligase HECT, UBA and WWE Domain Containing 1, (HUWE1) regulates key cancer-related pathways, including the Myc oncogene. It affects cell proliferation, stress and immune signaling, mitochondria homeostasis, and cell death. HUWE1 is evolutionarily conserved from Caenorhabditis...

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Detalles Bibliográficos
Autores principales:	Yanku, Yifat, Bitman-Lotan, Eliya, Zohar, Yaniv, Kurant, Estee, Zilke, Norman, Eilers, Martin, Orian, Amir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210797/ https://www.ncbi.nlm.nih.gov/pubmed/30261639 http://dx.doi.org/10.3390/cells7100151

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