Burkholderia Cepacia Endophthalmitis: An Unusual Presentation

PURPOSE: To report three cases of Burkholderia cepacia endophthalmitis following uneventful phacoemulsification surgery. CASE REPORT: Three cases presented with blurriness of vision 2 to 3 weeks following phacoemulsification. Vitreous culture confirmed the diagnosis. Pars plana vitrectomy with intravitreal injection of vancomycin (1 mg/0.1 ml) and ceftazidime (2.25 mg/0.1 ml) was performed. Despite several modalities of treatment, 2 cases did not respond to intravitreal antibiotics and vitrectomy. The first case ended up with phthisis bulbi and the second case underwent evisceration. One case improved after intravitreal injection of the first dose of antibiotic. CONCLUSION: B. cepacia endophthalmitis is rare and difficult to treat. More studies are necessary to understand the course and outcome of the infection.