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Seroreactivity and Risk Factors Associated with Coxiella burnetii Infection among Cattle Slaughterhouse Workers in South Korea

Q fever, caused by Coxiella burnetii, is a zoonotic disease that is an occupational hazard to people who work in close contact with animals or their carcasses. A nationwide serologic study among cattle slaughterhouse workers who were presumed to be at risk of having C. burnetii infection in South Ko...

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Autores principales: Park, Ji-Hyuk, Hwang, Seon Do, Acharya, Dilaram, Lee, Seung Hun, Hwang, Kyu Jam, Yoo, Seok-Ju, Lee, Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210963/
https://www.ncbi.nlm.nih.gov/pubmed/30332766
http://dx.doi.org/10.3390/ijerph15102264
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author Park, Ji-Hyuk
Hwang, Seon Do
Acharya, Dilaram
Lee, Seung Hun
Hwang, Kyu Jam
Yoo, Seok-Ju
Lee, Kwan
author_facet Park, Ji-Hyuk
Hwang, Seon Do
Acharya, Dilaram
Lee, Seung Hun
Hwang, Kyu Jam
Yoo, Seok-Ju
Lee, Kwan
author_sort Park, Ji-Hyuk
collection PubMed
description Q fever, caused by Coxiella burnetii, is a zoonotic disease that is an occupational hazard to people who work in close contact with animals or their carcasses. A nationwide serologic study among cattle slaughterhouse workers who were presumed to be at risk of having C. burnetii infection in South Korea was performed to investigate the seroreactivity of C. burnetii infection and identify related risk factors. Out of 1017 cattle slaughterhouse workers in South Korea, 923 (90.8%) participated in this cross-sectional study. Samples were tested for immunoglobulin G (IgG) and M (IgM) antibodies against phase II C. burnetii via indirect immunofluorescence assay. The overall seroreactivity, defined as IgG or IgM antibody titer cutoffs ≥1:16, was 9.1% (84/923). Additionally, a significant association was found between the seroreactivity of C. burnetii infection and performing carcass evisceration work (odds ratio, 2.36; 95% confidence interval, 1.39–4.03) in multivariate analysis. To diminish C. burnetii infection, cattle slaughterhouse workers need to take precautions during the evisceration process.
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spelling pubmed-62109632018-11-02 Seroreactivity and Risk Factors Associated with Coxiella burnetii Infection among Cattle Slaughterhouse Workers in South Korea Park, Ji-Hyuk Hwang, Seon Do Acharya, Dilaram Lee, Seung Hun Hwang, Kyu Jam Yoo, Seok-Ju Lee, Kwan Int J Environ Res Public Health Article Q fever, caused by Coxiella burnetii, is a zoonotic disease that is an occupational hazard to people who work in close contact with animals or their carcasses. A nationwide serologic study among cattle slaughterhouse workers who were presumed to be at risk of having C. burnetii infection in South Korea was performed to investigate the seroreactivity of C. burnetii infection and identify related risk factors. Out of 1017 cattle slaughterhouse workers in South Korea, 923 (90.8%) participated in this cross-sectional study. Samples were tested for immunoglobulin G (IgG) and M (IgM) antibodies against phase II C. burnetii via indirect immunofluorescence assay. The overall seroreactivity, defined as IgG or IgM antibody titer cutoffs ≥1:16, was 9.1% (84/923). Additionally, a significant association was found between the seroreactivity of C. burnetii infection and performing carcass evisceration work (odds ratio, 2.36; 95% confidence interval, 1.39–4.03) in multivariate analysis. To diminish C. burnetii infection, cattle slaughterhouse workers need to take precautions during the evisceration process. MDPI 2018-10-16 2018-10 /pmc/articles/PMC6210963/ /pubmed/30332766 http://dx.doi.org/10.3390/ijerph15102264 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Park, Ji-Hyuk
Hwang, Seon Do
Acharya, Dilaram
Lee, Seung Hun
Hwang, Kyu Jam
Yoo, Seok-Ju
Lee, Kwan
Seroreactivity and Risk Factors Associated with Coxiella burnetii Infection among Cattle Slaughterhouse Workers in South Korea
title Seroreactivity and Risk Factors Associated with Coxiella burnetii Infection among Cattle Slaughterhouse Workers in South Korea
title_full Seroreactivity and Risk Factors Associated with Coxiella burnetii Infection among Cattle Slaughterhouse Workers in South Korea
title_fullStr Seroreactivity and Risk Factors Associated with Coxiella burnetii Infection among Cattle Slaughterhouse Workers in South Korea
title_full_unstemmed Seroreactivity and Risk Factors Associated with Coxiella burnetii Infection among Cattle Slaughterhouse Workers in South Korea
title_short Seroreactivity and Risk Factors Associated with Coxiella burnetii Infection among Cattle Slaughterhouse Workers in South Korea
title_sort seroreactivity and risk factors associated with coxiella burnetii infection among cattle slaughterhouse workers in south korea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210963/
https://www.ncbi.nlm.nih.gov/pubmed/30332766
http://dx.doi.org/10.3390/ijerph15102264
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