Cargando…

The Interplay among PINK1/PARKIN/Dj-1 Network during Mitochondrial Quality Control in Cancer Biology: Protein Interaction Analysis

PARKIN (E3 ubiquitin ligase PARK2), PINK1 (PTEN induced kinase 1) and DJ-1 (PARK7) are proteins involved in autosomal recessive parkinsonism, and carcinogenic processes. In damaged mitochondria, PINK1’s importing into the inner mitochondrial membrane is prevented, PARKIN presents a partial mitochond...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salazar, Celia, Ruiz-Hincapie, Paula, Ruiz, Lina María
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210981/ https://www.ncbi.nlm.nih.gov/pubmed/30274236 http://dx.doi.org/10.3390/cells7100154

Ejemplares similares

Regulation of mitochondrial function by PINK1, Parkin and DJ-1
por: Giaime, Emilie, et al.
Publicado: (2013)

Hexokinases link DJ-1 to the PINK1/parkin pathway
por: Hauser, David N., et al.
Publicado: (2017)

Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection
por: Trempe, Jean-François, et al.
Publicado: (2013)

DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy
por: Imberechts, Dorien, et al.
Publicado: (2022)

Mitochondrial quality control beyond PINK1/Parkin
por: von Stockum, Sophia, et al.
Publicado: (2018)

PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease
por: Kazlauskaite, Agne, et al.
Publicado: (2015)

The contribution of Parkin, PINK1 and DJ‐1 genes to selective neuronal degeneration in Parkinson's disease
por: van der Vlag, Marc, et al.
Publicado: (2020)

PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control
por: Zhuang, Na, et al.
Publicado: (2016)

PINK1-Parkin Pathway Activity Is Regulated by Degradation of PINK1 in the Mitochondrial Matrix
por: Thomas, Ruth E., et al.
Publicado: (2014)

Exon Dosage Variations in Brazilian Patients with Parkinson’s Disease: Analysis of SNCA, PARKIN, PINK1 and DJ-1 Genes
por: Moura, Karla Cristina Vasconcelos, et al.
Publicado: (2012)

SWATH-MS proteome profiling data comparison of DJ-1, Parkin, and PINK1 knockout rat striatal mitochondria
por: Stauch, Kelly L., et al.
Publicado: (2016)

Phosphorylation of Mitochondrial Polyubiquitin by PINK1 Promotes Parkin Mitochondrial Tethering
por: Shiba-Fukushima, Kahori, et al.
Publicado: (2014)

Recognizing the cooperative and independent mitochondrial functions of Parkin and PINK1
por: Johnson, Bethann N., et al.
Publicado: (2012)

Pink1/Parkin link inflammation, mitochondrial stress, and neurodegeneration
por: Newman, Laura E., et al.
Publicado: (2018)

PINK1/PARKIN signalling in neurodegeneration and neuroinflammation
por: Quinn, Peter M. J., et al.
Publicado: (2020)

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin
por: Yun, Jina, et al.
Publicado: (2014)

Temporal integration of mitochondrial stress signals by the PINK1:Parkin pathway
por: Bowling, J. Logan, et al.
Publicado: (2019)

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
por: Matsuda, Noriyuki, et al.
Publicado: (2010)

PINK1-Mediated Phosphorylation of Parkin Boosts Parkin Activity in Drosophila
por: Shiba-Fukushima, Kahori, et al.
Publicado: (2014)

Clueless, a protein required for mitochondrial function, interacts with the PINK1-Parkin complex in Drosophila
por: Sen, Aditya, et al.
Publicado: (2015)

PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease
por: Ge, Preston, et al.
Publicado: (2020)

The Roles of PINK1 and Parkin in Parkinson's Disease
por: Jones, Rachel
Publicado: (2010)

PINK1 and Parkin to control mitochondria remodeling
por: Koh, Hyongjong, et al.
Publicado: (2010)

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
por: Shiba-Fukushima, Kahori, et al.
Publicado: (2012)

New Perception of Mitochondrial Regulatory Pathway in Parkinsonism – Ubiquitin, PINK1, and Parkin
por: Olszewska, Diana Angelika, et al.
Publicado: (2014)

PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes
por: Kubli, Dieter A., et al.
Publicado: (2015)

Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin‐mediated mitophagy
por: Ivankovic, Davor, et al.
Publicado: (2015)

PINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease
por: Mouton-Liger, Francois, et al.
Publicado: (2017)

Cannabidiol activates PINK1-Parkin-dependent mitophagy and mitochondrial-derived vesicles
por: Ramirez, Adrian, et al.
Publicado: (2022)

PINK1/Parkin Pathway Activation for Mitochondrial Quality Control – Which Is the Best Molecular Target for Therapy?
por: Silvian, Laura F.
Publicado: (2022)

Reduction of PINK1 or DJ‐1 impair mitochondrial motility in neurites and alter ER‐mitochondria contacts
por: Parrado‐Fernández, Cristina, et al.
Publicado: (2018)

Mitophagy and Parkinson's disease: The PINK1–parkin link()
por: Deas, Emma, et al.
Publicado: (2011)

Parkin and PINK1 mitigate STING-induced inflammation
por: Sliter, Danielle A., et al.
Publicado: (2018)

Response to Rotenone Is Glucose-Sensitive in a Model of Human Acute Lymphoblastic Leukemia: Involvement of Oxidative Stress Mechanism, DJ-1, Parkin, and PINK-1 Proteins
por: Mendivil-Perez, Miguel, et al.
Publicado: (2014)

The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway
por: Poole, Angela C., et al.
Publicado: (2010)

Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1
por: Burbulla, L F, et al.
Publicado: (2014)

Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system
por: McLelland, Gian-Luca, et al.
Publicado: (2016)

PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?
por: Truban, Dominika, et al.
Publicado: (2017)

DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria
por: Ozawa, Kentaro, et al.
Publicado: (2020)

Unaltered Striatal Dopamine Release Levels in Young Parkin Knockout, Pink1 Knockout, DJ-1 Knockout and LRRK2 R1441G Transgenic Mice
por: Sanchez, Gonzalo, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ludjkkjdmc9g9f89qhmv3pnocb