Comprehensive Analysis of Germline Variants in Mexican Patients with Hereditary Breast and Ovarian Cancer Susceptibility

Hereditary breast and ovarian cancer syndrome (HBOC) represents 5–10% of all patients with breast cancer and is associated with high-risk pathogenic alleles in BRCA1/2 genes, but only for 25% of cases. We aimed to find new pathogenic alleles in a panel of 143 cancer-predisposing genes in 300 Mexican...

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Detalles Bibliográficos
Autores principales: Quezada Urban, Rosalía, Díaz Velásquez, Clara Estela, Gitler, Rina, Rojo Castillo, María Patricia, Sirota Toporek, Max, Figueroa Morales, Andrea, Moreno García, Oscar, García Esquivel, Lizbeth, Torres Mejía, Gabriela, Dean, Michael, Delgado Enciso, Iván, Ochoa Díaz López, Héctor, Rodríguez León, Fernando, Jan, Virginia, Garzón Barrientos, Víctor Hugo, Ruiz Flores, Pablo, Espino Silva, Perla Karina, Haro Santa Cruz, Jorge, Martínez Gregorio, Héctor, Rojas Jiménez, Ernesto Arturo, Romero Cruz, Luis Enrique, Méndez Catalá, Claudia Fabiola, Álvarez Gómez, Rosa María, Fragoso Ontiveros, Verónica, Herrera, Luis Alonso, Romieu, Isabelle, Terrazas, Luis Ignacio, Chirino, Yolanda Irasema, Frecha, Cecilia, Oliver, Javier, Perdomo, Sandra, Vaca Paniagua, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211045/
https://www.ncbi.nlm.nih.gov/pubmed/30262796
http://dx.doi.org/10.3390/cancers10100361

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