Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes

Radical oxygen species formed in human tissue cells by many endogenous and exogenous pathways cause extensive oxidative damage which has been linked to various human diseases. This review paper provides an overview of lipid peroxidation and focuses on the free radicals-initiated processes of low-den...

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Detalles Bibliográficos
Autores principales: Kiokias, Sotirios, Proestos, Charalampos, Oreopoulou, Vassilki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211048/
https://www.ncbi.nlm.nih.gov/pubmed/30282925
http://dx.doi.org/10.3390/antiox7100133
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author Kiokias, Sotirios
Proestos, Charalampos
Oreopoulou, Vassilki
author_facet Kiokias, Sotirios
Proestos, Charalampos
Oreopoulou, Vassilki
author_sort Kiokias, Sotirios
collection PubMed
description Radical oxygen species formed in human tissue cells by many endogenous and exogenous pathways cause extensive oxidative damage which has been linked to various human diseases. This review paper provides an overview of lipid peroxidation and focuses on the free radicals-initiated processes of low-density lipoprotein (LDL) oxidative modification and DNA oxidative damage, which are widely associated with the initiation and development of atherosclerosis and carcinogenesis, respectively. The article subsequently provides an overview of the recent human trials or even in vitro investigations on the potential of natural antioxidant compounds (such as carotenoids; vitamins C and E) to monitor LDL and DNA oxidative changes.
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spelling pubmed-62110482018-11-05 Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes Kiokias, Sotirios Proestos, Charalampos Oreopoulou, Vassilki Antioxidants (Basel) Review Radical oxygen species formed in human tissue cells by many endogenous and exogenous pathways cause extensive oxidative damage which has been linked to various human diseases. This review paper provides an overview of lipid peroxidation and focuses on the free radicals-initiated processes of low-density lipoprotein (LDL) oxidative modification and DNA oxidative damage, which are widely associated with the initiation and development of atherosclerosis and carcinogenesis, respectively. The article subsequently provides an overview of the recent human trials or even in vitro investigations on the potential of natural antioxidant compounds (such as carotenoids; vitamins C and E) to monitor LDL and DNA oxidative changes. MDPI 2018-10-03 /pmc/articles/PMC6211048/ /pubmed/30282925 http://dx.doi.org/10.3390/antiox7100133 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kiokias, Sotirios
Proestos, Charalampos
Oreopoulou, Vassilki
Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes
title Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes
title_full Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes
title_fullStr Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes
title_full_unstemmed Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes
title_short Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes
title_sort effect of natural food antioxidants against ldl and dna oxidative changes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211048/
https://www.ncbi.nlm.nih.gov/pubmed/30282925
http://dx.doi.org/10.3390/antiox7100133
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