Cargando…

H19 Is Expressed in Hybrid Hepatocyte Nuclear Factor 4α(+) Periportal Hepatocytes but Not Cytokeratin 19(+) Cholangiocytes in Cholestatic Livers

Long noncoding RNA (lncRNA) H19 is abundantly expressed in fetal liver. Its expression is significantly diminished in adult healthy liver but is re‐induced in chronic liver diseases, including cholestasis. In this study, we developed a new method with combined in situ hybridization (ISH) and immunof...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, YanChao, Huang, Yi, Cai, ShiYing, Song, YongFeng, Boyer, James L., Zhang, KeZhong, Gao, Ling, Zhao, JiaJun, Huang, WenDong, Liang, Guang, Liangpunsakul, Suthat, Wang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211330/ https://www.ncbi.nlm.nih.gov/pubmed/30411082 http://dx.doi.org/10.1002/hep4.1252

Ejemplares similares

Intrabiliary infusion of naked DNA vectors targets periportal hepatocytes in mice
por: Deplazes, Sereina, et al.
Publicado: (2022)

Periportal hepatocyte proliferation at midgestation governs maternal glucose homeostasis in mice
por: Kozuki, Satoshi, et al.
Publicado: (2023)

Hepatocyte‐Specific β‐Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes
por: Russell, Jacquelyn O., et al.
Publicado: (2019)

Atypical cholangiocytes derived from hepatocyte-cholangiocyte transdifferentiation mediated by COX-2: a kind of misguided liver regeneration
por: Lan, Tian, et al.
Publicado: (2023)

IL‐8 induces transdifferentiation of mature hepatocytes toward the cholangiocyte phenotype
por: Sasaki, Tokio, et al.
Publicado: (2019)

DHEA Protects Human Cholangiocytes and Hepatocytes against Apoptosis and Oxidative Stress
por: Kilanczyk, Ewa, et al.
Publicado: (2022)

Cholangiocytes act as Facultative Liver Stem Cells during Impaired Hepatocyte Regeneration
por: Raven, Alexander, et al.
Publicado: (2017)

Dynamics of hepatocyte-cholangiocyte cell-fate decisions during liver development and regeneration
por: Sahoo, Sarthak, et al.
Publicado: (2022)

Feeding and fasting controls liver expression of a regulator of G protein signaling (Rgs16) in periportal hepatocytes
por: Huang, Jie, et al.
Publicado: (2006)

Protective effects of catalpol on mitochondria of hepatocytes in cholestatic liver injury
por: Gao, Xingjuan, et al.
Publicado: (2020)

PGC-1α Promotes Ureagenesis in Mouse Periportal Hepatocytes through SIRT3 and SIRT5 in Response to Glucagon
por: Li, Lulu, et al.
Publicado: (2016)

Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo
por: Tanimizu, Naoki, et al.
Publicado: (2021)

Successful Derivation of Hepatoblasts, Cholangiocytes and Hepatocytes from Simian Induced Pluripotent Stem Cells
por: Luce, Eleanor, et al.
Publicado: (2022)

Long non-coding RNAs in liver diseases: Focusing on nonalcoholic fatty liver disease, alcohol-related liver disease, and cholestatic liver disease
por: Han, Sen, et al.
Publicado: (2020)

Hepatocyte-Specific Depletion of UBXD8 Induces Periportal Steatosis in Mice Fed a High-Fat Diet
por: Imai, Norihiro, et al.
Publicado: (2015)

Increased microfilaments in hepatocytes and biliary ductular cells in cholestatic liver diseases.
por: Chung, Kyu-Won, et al.
Publicado: (2002)

Focal overexpression of insulin-like growth factor 2 by hepatocytes and cholangiocytes in viral liver cirrhosis
por: Sedlaczek, N, et al.
Publicado: (2003)

Transmembrane channel activity in human hepatocytes and cholangiocytes derived from induced pluripotent stem cells
por: Florentino, Rodrigo M., et al.
Publicado: (2022)

Correction: Hepatocyte-Specific Depletion of UBXD8 Induces Periportal Steatosis in Mice Fed a High-Fat Diet
por: Imai, Norihiro, et al.
Publicado: (2016)

Aberrant cytokeratin 7 expression by hepatocytes can predict the ductopenia grade in primary biliary cholangitis
por: Liu, Hong-Li, et al.
Publicado: (2022)

An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cells
por: Boteon, Yuri L., et al.
Publicado: (2018)

Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease
por: Lemberger, Ursula J., et al.
Publicado: (2016)

Single-Cell Transcriptomes Reveal Characteristic Features of Mouse Hepatocytes with Liver Cholestatic Injury
por: Chang, Na, et al.
Publicado: (2019)

Cholangiocyte-Derived Exosomal lncRNA H19 Promotes Macrophage Activation and Hepatic Inflammation under Cholestatic Conditions
por: Li, Xiaojiaoyang, et al.
Publicado: (2020)

p-STAT3 is a PDC-E2 interacting partner in human cholangiocytes and hepatocytes with potential pathobiological implications
por: Kilanczyk, Ewa, et al.
Publicado: (2021)

ZO-2/Tjp2 suppresses Yap and Wwtr1/Taz-mediated hepatocyte to cholangiocyte transdifferentiation in the mouse liver
por: Xu, Jianliang, et al.
Publicado: (2022)

Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice
por: Delhove, Juliette M. K. M., et al.
Publicado: (2017)

Metabolic nuclear receptors coordinate energy metabolism to regulate Sox9(+) hepatocyte fate
por: Liu, Shenghui, et al.
Publicado: (2021)

Immunohistochemical study of hepatocyte, cholangiocyte and stem cell markers of hepatocellular carcinoma: the second report: relationship with tumor size and cell differentiation
por: Kumagai, Arisa, et al.
Publicado: (2016)

MiR-200c-3p targets SESN1 and represses the IL-6/AKT loop to prevent cholangiocyte activation and cholestatic liver fibrosis
por: Song, Yongfeng, et al.
Publicado: (2021)

The Efficacy of the Hepatocyte Spheroids for Hepatocyte Transplantation
por: Shibuya, Kazuaki, et al.
Publicado: (2021)

Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases
por: Guldiken, Nurdan, et al.
Publicado: (2021)

Knockout of α-calcitonin gene-related peptide attenuates cholestatic liver injury by differentially regulating cellular senescence of hepatic stellate cells and cholangiocytes
por: Wan, Ying, et al.
Publicado: (2019)

Loss of nuclear PTEN in HCV-infected human hepatocytes
por: Bao, Wenjie, et al.
Publicado: (2014)

Generation of functional hepatocytes by forward programming with nuclear receptors
por: Tomaz, Rute A, et al.
Publicado: (2022)

Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model
por: Ni, Xuan, et al.
Publicado: (2016)

Inhibition of NLRP3-mediated crosstalk between hepatocytes and liver macrophages by geniposidic acid alleviates cholestatic liver inflammatory injury
por: Song, Meng, et al.
Publicado: (2022)

Novel sericin-based hepatocyte serum-free medium and sericin’s effect on hepatocyte transcriptome
por: Huang, Yun, et al.
Publicado: (2018)

Hepatocyte apoptosis fragment product cytokeratin-18 M30 level and non-alcoholic steatohepatitis risk diagnosis: an international registry study
por: Zhang, Huai, et al.
Publicado: (2023)

Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2(−/−) mouse model of primary sclerosing cholangitis (PSC)
por: Zhou, Tianhao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_p6cdhblrfgs1a35056qv8c0sic