Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs

Three variants of the multidrug-resistant plasmid pLUH01 were assembled by deep sequencing from nasopharyngeal swabs. All have a 21-bp deletion in the RS14515 hypothetical gene. Variants 1 through 3 have 2, 6, and 3 nucleotide substitutions, respectively, compared to the pLUH01 reference genome. We...

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Autores principales: Atkinson, Kate V., Bishop, Lisa A., Rhodes, Glenn, Salez, Nicolas, McEwan, Neil R., Hegarty, Matthew J., Robey, Julie, Harding, Nicola, Wetherell, Simon, Lauder, Robert M., Pickup, Roger W., Wilkinson, Mark, Gatherer, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Other Genetic Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211343/
https://www.ncbi.nlm.nih.gov/pubmed/30533609
http://dx.doi.org/10.1128/MRA.00835-18
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author Atkinson, Kate V.
Bishop, Lisa A.
Rhodes, Glenn
Salez, Nicolas
McEwan, Neil R.
Hegarty, Matthew J.
Robey, Julie
Harding, Nicola
Wetherell, Simon
Lauder, Robert M.
Pickup, Roger W.
Wilkinson, Mark
Gatherer, Derek
author_facet Atkinson, Kate V.
Bishop, Lisa A.
Rhodes, Glenn
Salez, Nicolas
McEwan, Neil R.
Hegarty, Matthew J.
Robey, Julie
Harding, Nicola
Wetherell, Simon
Lauder, Robert M.
Pickup, Roger W.
Wilkinson, Mark
Gatherer, Derek
author_sort Atkinson, Kate V.
collection PubMed
description Three variants of the multidrug-resistant plasmid pLUH01 were assembled by deep sequencing from nasopharyngeal swabs. All have a 21-bp deletion in the RS14515 hypothetical gene. Variants 1 through 3 have 2, 6, and 3 nucleotide substitutions, respectively, compared to the pLUH01 reference genome. We named the new plasmid variants pLUH01/Lancaster/2015/1 to pLUH01/Lancaster/2015/3.
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spelling pubmed-62113432018-12-07 Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs Atkinson, Kate V. Bishop, Lisa A. Rhodes, Glenn Salez, Nicolas McEwan, Neil R. Hegarty, Matthew J. Robey, Julie Harding, Nicola Wetherell, Simon Lauder, Robert M. Pickup, Roger W. Wilkinson, Mark Gatherer, Derek Microbiol Resour Announc Other Genetic Resources Three variants of the multidrug-resistant plasmid pLUH01 were assembled by deep sequencing from nasopharyngeal swabs. All have a 21-bp deletion in the RS14515 hypothetical gene. Variants 1 through 3 have 2, 6, and 3 nucleotide substitutions, respectively, compared to the pLUH01 reference genome. We named the new plasmid variants pLUH01/Lancaster/2015/1 to pLUH01/Lancaster/2015/3. American Society for Microbiology 2018-07-12 /pmc/articles/PMC6211343/ /pubmed/30533609 http://dx.doi.org/10.1128/MRA.00835-18 Text en Copyright © 2018 Atkinson et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Other Genetic Resources
Atkinson, Kate V.
Bishop, Lisa A.
Rhodes, Glenn
Salez, Nicolas
McEwan, Neil R.
Hegarty, Matthew J.
Robey, Julie
Harding, Nicola
Wetherell, Simon
Lauder, Robert M.
Pickup, Roger W.
Wilkinson, Mark
Gatherer, Derek
Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs
title Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs
title_full Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs
title_fullStr Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs
title_full_unstemmed Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs
title_short Sequence Variation in Multidrug-Resistant Plasmid pLUH01, Isolated from Human Nasopharyngeal Swabs
title_sort sequence variation in multidrug-resistant plasmid pluh01, isolated from human nasopharyngeal swabs
topic Other Genetic Resources
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211343/
https://www.ncbi.nlm.nih.gov/pubmed/30533609
http://dx.doi.org/10.1128/MRA.00835-18
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