Biological single-particle imaging using XFELs – towards the next resolution revolution

Better injectors resulting from careful iterative optimization used at high repetition XFELs in combination with better detectors and further developed algorithms might, in the not so distant future, result in a ‘resolution revolution’ in SPI, enabling the molecular and atomic imaging of the dynamic...

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Detalles Bibliográficos
Autor principal: Oberthür, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Scientific Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211524/
https://www.ncbi.nlm.nih.gov/pubmed/30443350
http://dx.doi.org/10.1107/S2052252518015129
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author Oberthür, Dominik
author_facet Oberthür, Dominik
author_sort Oberthür, Dominik
collection PubMed
description Better injectors resulting from careful iterative optimization used at high repetition XFELs in combination with better detectors and further developed algorithms might, in the not so distant future, result in a ‘resolution revolution’ in SPI, enabling the molecular and atomic imaging of the dynamics of biological macromolecules without the need to freeze or crystallize the sample.
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spelling pubmed-62115242018-11-15 Biological single-particle imaging using XFELs – towards the next resolution revolution Oberthür, Dominik IUCrJ Scientific Commentaries Better injectors resulting from careful iterative optimization used at high repetition XFELs in combination with better detectors and further developed algorithms might, in the not so distant future, result in a ‘resolution revolution’ in SPI, enabling the molecular and atomic imaging of the dynamics of biological macromolecules without the need to freeze or crystallize the sample. International Union of Crystallography 2018-10-31 /pmc/articles/PMC6211524/ /pubmed/30443350 http://dx.doi.org/10.1107/S2052252518015129 Text en © Dominik Oberthür 2018 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/2.0/uk/
spellingShingle Scientific Commentaries
Oberthür, Dominik
Biological single-particle imaging using XFELs – towards the next resolution revolution
title Biological single-particle imaging using XFELs – towards the next resolution revolution
title_full Biological single-particle imaging using XFELs – towards the next resolution revolution
title_fullStr Biological single-particle imaging using XFELs – towards the next resolution revolution
title_full_unstemmed Biological single-particle imaging using XFELs – towards the next resolution revolution
title_short Biological single-particle imaging using XFELs – towards the next resolution revolution
title_sort biological single-particle imaging using xfels – towards the next resolution revolution
topic Scientific Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211524/
https://www.ncbi.nlm.nih.gov/pubmed/30443350
http://dx.doi.org/10.1107/S2052252518015129
work_keys_str_mv AT oberthurdominik biologicalsingleparticleimagingusingxfelstowardsthenextresolutionrevolution

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