Orally administered gold nanoparticles protect against colitis by attenuating Toll-like receptor 4- and reactive oxygen/nitrogen species-mediated inflammatory responses but could induce gut dysbiosis in mice

BACKGROUND: Gold nanoparticles (AuNPs) are attracting interest as potential therapeutic agents to treat inflammatory diseases, but their anti-inflammatory mechanism of action is not clear yet. In addition, the effect of orally administered AuNPs on gut microbiota has been overlooked so far. Here, we...

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Detalles Bibliográficos
Autores principales: Zhu, Suqin, Jiang, Xiumei, Boudreau, Mary D., Feng, Guangxin, Miao, Yu, Dong, Shiyuan, Wu, Haohao, Zeng, Mingyong, Yin, Jun-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211593/
https://www.ncbi.nlm.nih.gov/pubmed/30384844
http://dx.doi.org/10.1186/s12951-018-0415-5

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