Cargando…

Lymphopenia and risk of infection and infection-related death in 98,344 individuals from a prospective Danish population-based study

BACKGROUND: Neutropenia increases the risk of infection, but it is unknown if this also applies to lymphopenia. We therefore tested the hypotheses that lymphopenia is associated with increased risk of infection and infection-related death in the general population. METHODS AND FINDINGS: Of the invit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Warny, Marie, Helby, Jens, Nordestgaard, Børge Grønne, Birgens, Henrik, Bojesen, Stig Egil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211632/ https://www.ncbi.nlm.nih.gov/pubmed/30383787 http://dx.doi.org/10.1371/journal.pmed.1002685

Ejemplares similares

S280: INDIVIDUALS WITH HFE C282Y HOMOZYGOSITY AND DIABETES HAVE ALMOST TWO-FOLD RISK OF DEATH COMPARED TO NON-CARRIERS WITH DIABETES: A PROSPECTIVE STUDY OF A 132,542-INDIVIDUAL GENERAL POPULATION COHORT
por: Mottelson, Mathis, et al.
Publicado: (2023)

Shorter leukocyte telomere length is associated with higher risk of infections: a prospective study of 75,309 individuals from the general population
por: Helby, Jens, et al.
Publicado: (2017)

Low high-density lipoprotein and increased risk of several cancers: 2 population-based cohort studies including 116,728 individuals
por: Pedersen, Kasper Mønsted, et al.
Publicado: (2020)

Tumor suppressor p53 Arg72Pro polymorphism and longevity, cancer survival, and risk of cancer in the general population
por: Ørsted, David Dynnes, et al.
Publicado: (2007)

Tocilizumab and soluble interleukin-6 receptor in JAK2V617F somatic mutation and myeloproliferative neoplasm
por: Pedersen, Kasper Mønsted, et al.
Publicado: (2020)

Two-fold risk of pneumonia and respiratory mortality in individuals with myeloproliferative neoplasm: A population-based cohort study
por: Pedersen, Kasper Mønsted, et al.
Publicado: (2020)

Loss-of-function polymorphism in IL6R reduces risk of JAK2V617F somatic mutation and myeloproliferative neoplasm: A Mendelian randomization study
por: Pedersen, Kasper Mønsted, et al.
Publicado: (2020)

Secular trends in smoking in relation to prevalent and incident smoking-related disease: A prospective population-based study
por: Tonnesen, Philip, et al.
Publicado: (2019)

Response to Comment on: Ellervik et al. Elevated Transferrin Saturation and Risk of Diabetes: Three Population-Based Studies. Diabetes Care 2011;34:2256–2258
por: Ellervik, Christina, et al.
Publicado: (2012)

Elevated pre-treatment levels of plasma C-reactive protein are associated with poor prognosis after breast cancer: a cohort study
por: Allin, Kristine H, et al.
Publicado: (2011)

Telomere Shortening Unrelated to Smoking, Body Weight, Physical Activity, and Alcohol Intake: 4,576 General Population Individuals with Repeat Measurements 10 Years Apart
por: Weischer, Maren, et al.
Publicado: (2014)

Impact of the metabolic syndrome on cardiopulmonary morbidity and mortality in individuals with lung function impairment: a prospective cohort study of the Danish general population
por: Marott, Jacob Louis, et al.
Publicado: (2023)

Genetic dissection of lymphopenia from autoimmunity by introgression of mutated Ian5 gene onto the F344 rat
por: Moralejo, Daniel H., et al.
Publicado: (2003)

Elevated rheumatoid factor and long term risk of rheumatoid arthritis: a prospective cohort study
por: Nielsen, Sune F, et al.
Publicado: (2012)

Genetically low vitamin D concentrations and increased mortality: mendelian randomisation analysis in three large cohorts
por: Afzal, Shoaib, et al.
Publicado: (2014)

Physical activity and risk of instant and 28-day case-fatality in myocardial infarction
por: Peytz, Nina Caroline, et al.
Publicado: (2019)

Elevated Transferrin Saturation and Risk of Diabetes: Three population-based studies
por: Ellervik, Christina, et al.
Publicado: (2011)

Total Mortality by Elevated Transferrin Saturation in Patients With Diabetes
por: Ellervik, Christina, et al.
Publicado: (2013)

AHRR (cg05575921) hypomethylation marks smoking behaviour, morbidity and mortality
por: Bojesen, Stig E, et al.
Publicado: (2017)

Lymphopenia Caused by Virus Infections and the Mechanisms Beyond
por: Guo, Zijing, et al.
Publicado: (2021)

The physical activity paradox in cardiovascular disease and all-cause mortality: the contemporary Copenhagen General Population Study with 104 046 adults
por: Holtermann, Andreas, et al.
Publicado: (2021)

Lymphopenia, Lymphopenia-Induced Proliferation, and Autoimmunity
por: Sheu, Ting-Ting, et al.
Publicado: (2021)

TP53 Arg72Pro, mortality after cancer, and all-cause mortality in 105,200 individuals
por: Kodal, Jakob B., et al.
Publicado: (2017)

ABCA7 and risk of dementia and vascular disease in the Danish population
por: Kjeldsen, Emilie W., et al.
Publicado: (2017)

Pre-Existing Lymphopenia Increases the Risk of Hospitalization and Death after SARS-CoV-2 Infection
por: Garbo, Riccardo, et al.
Publicado: (2022)

Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration
por: Nordestgaard, Liv Tybjærg, et al.
Publicado: (2023)

Association between low density lipoprotein and all cause and cause specific mortality in Denmark: prospective cohort study
por: Johannesen, Camilla Ditlev Lindhardt, et al.
Publicado: (2020)

Causal risk factors for asthma in Mendelian randomization studies: A systematic review and meta‐analysis
por: Mikkelsen, Heidi, et al.
Publicado: (2022)

P1484: THE DANISH SCREENING PROGRAM FOR HEMOGLOBINOPATHIES: A 16-YEAR REVIEW
por: Gravholt, Esther, et al.
Publicado: (2023)

Persistent lymphopenia is a risk factor for ICU-acquired infections and for death in ICU patients with sustained hypotension at admission
por: Adrie, Christophe, et al.
Publicado: (2017)

Poor Prognosis for Puumala Virus Infections Predicted by Lymphopenia and Dyspnea
por: Hatzl, Stefan, et al.
Publicado: (2023)

Inflammatory Biomarker Score Identifies Patients with Six-Fold Increased Risk of One-Year Mortality after Pancreatic Cancer
por: Kjaergaard, Alisa D., et al.
Publicado: (2021)

Coronary heart disease and heart failure in asthma, COPD and asthma-COPD overlap
por: Ingebrigtsen, Truls Sylvan, et al.
Publicado: (2020)

Low levels of small HDL particles predict but do not influence risk of sepsis
por: Hamilton, Fergus, et al.
Publicado: (2023)

Lymphopenia in SARS
por: Panesar, Nirmal S
Publicado: (2003)

The Danish comorbidity in liver transplant recipients study (DACOLT): a non-interventional prospective observational cohort study
por: Thomsen, Magda Teresa, et al.
Publicado: (2021)

Clonal haematopoiesis of indeterminate potential and impaired kidney function—A Danish general population study with 11 years follow‐up
por: Larsen, Morten K., et al.
Publicado: (2022)

Corticosteroids Augment BRAF Inhibitor Vemurafenib Induced Lymphopenia and Risk of Infection
por: Sondermann, Wiebke, et al.
Publicado: (2015)

HIV infection compounds the lymphopenia associated with cerebral malaria in Malawian children
por: Mandala, Wilson L, et al.
Publicado: (2018)

Fingolimod: Lymphopenia and COVID-19 infection complicated by pneumonia: case report
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_93a8jujbte6m63jeu0rq7cpca0