Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians

Centenarians (CENs) are excellent subjects to study the mechanisms of human longevity and healthy aging. Here, we analyzed the transcriptomes of 76 centenarians, 54 centenarian-children, and 41 spouses of centenarian-children by RNA sequencing and found that, among the significantly differentially e...

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Detalles Bibliográficos
Autores principales: Xiao, Fu-Hui, Chen, Xiao-Qiong, Yu, Qin, Ye, Yunshuang, Liu, Yao-Wen, Yan, Dongjing, Yang, Li-Qin, Chen, Guijun, Lin, Rong, Yang, Liping, Liao, Xiaoping, Zhang, Wen, Zhang, Wei, Tang, Nelson Leung-Sang, Wang, Xiao-Fan, Zhou, Jumin, Cai, Wang-Wei, He, Yong-Han, Kong, Qing-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211641/
https://www.ncbi.nlm.nih.gov/pubmed/30352807
http://dx.doi.org/10.1101/gr.220780.117

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