Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer’s disease and normalized by treatment with anti-diabetic agents

A large body of literature links risk of cognitive decline, mild cognitive impairment (MCI) and dementia with Type 2 Diabetes (T2D) or pre-diabetes. Accumulating evidence implicates a close relationship between the brain insulin receptor signaling pathway (IRSP) and the accumulation of amyloid beta...

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Detalles Bibliográficos
Autores principales: Katsel, P., Roussos, P., Beeri, M. S., Gama-Sosa, M. A., Gandy, S., Khan, S., Haroutunian, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211704/
https://www.ncbi.nlm.nih.gov/pubmed/30383799
http://dx.doi.org/10.1371/journal.pone.0206547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211704/
https://www.ncbi.nlm.nih.gov/pubmed/30383799
http://dx.doi.org/10.1371/journal.pone.0206547

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