The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function

Different microRNAs (miRNAs), including miR-29 family, may play a role in the development of heart failure (HF), but the underlying molecular mechanisms in HF pathogenesis remain unclear. We aimed at characterizing mice deficient in miR-29 in order to address the functional relevance of this family...

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Detalles Bibliográficos
Autores principales: Caravia, Xurde M., Fanjul, Víctor, Oliver, Eduardo, Roiz-Valle, David, Morán-Álvarez, Alba, Desdín-Micó, Gabriela, Mittelbrunn, María, Cabo, Roberto, Vega, José A., Rodríguez, Francisco, Fueyo, Antonio, Gómez, Mónica, Lobo-González, Manuel, Bueno, Héctor, Velasco, Gloria, Freije, José M. P., Andrés, Vicente, Ibáñez, Borja, Ugalde, Alejandro P., López-Otín, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211751/
https://www.ncbi.nlm.nih.gov/pubmed/30346946
http://dx.doi.org/10.1371/journal.pbio.2006247

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