Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa

Pseudomonas aeruginosa utilizes the Type II secretion system (T2SS) to translocate a wide range of large, structured protein virulence factors through the periplasm to the extracellular environment for infection. In the T2SS, five pseudopilins assemble into the pseudopilus that acts as a piston to e...

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Detalles Bibliográficos
Autores principales: Zhang, Yichen, Faucher, Frédérick, Zhang, Wenwen, Wang, Shu, Neville, Nolan, Poole, Keith, Zheng, Jun, Jia, Zongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211770/
https://www.ncbi.nlm.nih.gov/pubmed/30346996
http://dx.doi.org/10.1371/journal.ppat.1007343

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