Acute microglia ablation induces neurodegeneration in the somatosensory system

Previous studies have reported that microglia depletion leads to impairment of synapse formation and these cells rapidly repopulate from CNS progenitors. However, the impact of microglia depletion and repopulation in the long-term state of the CNS environment has not been characterized. Here, we rep...

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Detalles Bibliográficos
Autores principales: Rubino, Stephen J., Mayo, Lior, Wimmer, Isabella, Siedler, Victoria, Brunner, Florian, Hametner, Simon, Madi, Asaf, Lanser, Amanda, Moreira, Thais, Donnelly, Dustin, Cox, Laura, Rezende, Rafael Machado, Butovsky, Oleg, Lassmann, Hans, Weiner, Howard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212411/
https://www.ncbi.nlm.nih.gov/pubmed/30385785
http://dx.doi.org/10.1038/s41467-018-05929-4

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