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GREB1 is an estrogen receptor-regulated tumour promoter that is frequently expressed in ovarian cancer

Estrogenic hormone replacement therapy increases the risk of developing ovarian cancer, and estrogen promotes tumour initiation and growth in mouse models of this disease. GREB1 (Growth regulation by estrogen in breast cancer 1) is an ESR1 (estrogen receptor 1)-upregulated protein which may mediate...

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Detalles Bibliográficos
Autores principales: Hodgkinson, Kendra, Forrest, Laura A., Vuong, Nhung, Garson, Kenneth, Djordjevic, Bojana, Vanderhyden, Barbara C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212416/
https://www.ncbi.nlm.nih.gov/pubmed/29973689
http://dx.doi.org/10.1038/s41388-018-0377-y