Progressive impairment of directional and spatially precise trajectories by TgF344-Alzheimer’s disease rats in the Morris Water Task

Spatial navigation is impaired in early stages of Alzheimer’s disease, and may be a defining behavioral marker of preclinical AD. A new rat model (TgF344-AD) of AD overcomes many limitations of other rodent models, though spatial navigation has not been comprehensively assessed. Using the hidden and...

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Detalles Bibliográficos
Autores principales: Berkowitz, Laura E., Harvey, Ryan E., Drake, Emma, Thompson, Shannon M., Clark, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212523/
https://www.ncbi.nlm.nih.gov/pubmed/30385825
http://dx.doi.org/10.1038/s41598-018-34368-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212523/
https://www.ncbi.nlm.nih.gov/pubmed/30385825
http://dx.doi.org/10.1038/s41598-018-34368-w

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