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Design of metalloproteins and novel protein folds using variational autoencoders
The design of novel proteins has many applications but remains an attritional process with success in isolated cases. Meanwhile, deep learning technologies have exploded in popularity in recent years and are increasingly applicable to biology due to the rise in available data. We attempt to link pro...
Autores principales: | Greener, Joe G., Moffat, Lewis, Jones, David T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212568/ https://www.ncbi.nlm.nih.gov/pubmed/30385875 http://dx.doi.org/10.1038/s41598-018-34533-1 |
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