Keeping up with the prostate-specific membrane antigens (PSMAs): an introduction to a new class of positron emission tomography (PET) imaging agents

Prostate-specific membrane antigen (PSMA) targeted positron emission tomography (PET) is an emerging prostate cancer imaging method, which has been reported to have a higher sensitivity and specificity than the currently approved PET imaging agents. Multiple PSMA ligands are being investigated aroun...

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Autores principales: Czarniecki, Marcin, Mena, Esther, Lindenberg, Liza, Cacko, Marek, Harmon, Stephanie, Radtke, Jan Philipp, Giesel, Frederick, Turkbey, Baris, Choyke, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212618/
https://www.ncbi.nlm.nih.gov/pubmed/30456186
http://dx.doi.org/10.21037/tau.2018.08.03
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author Czarniecki, Marcin
Mena, Esther
Lindenberg, Liza
Cacko, Marek
Harmon, Stephanie
Radtke, Jan Philipp
Giesel, Frederick
Turkbey, Baris
Choyke, Peter L.
author_facet Czarniecki, Marcin
Mena, Esther
Lindenberg, Liza
Cacko, Marek
Harmon, Stephanie
Radtke, Jan Philipp
Giesel, Frederick
Turkbey, Baris
Choyke, Peter L.
author_sort Czarniecki, Marcin
collection PubMed
description Prostate-specific membrane antigen (PSMA) targeted positron emission tomography (PET) is an emerging prostate cancer imaging method, which has been reported to have a higher sensitivity and specificity than the currently approved PET imaging agents. Multiple PSMA ligands are being investigated around the world and applications range from primary tumor characterization, to local staging, biochemical recurrence, metastasis, and image-guided interventions. The most investigated PET tracers are labelled with 68-Gallium or 18-Fluoride and are discussed in this review. Additionally, (99m)Tc labeled PSMA agents for single photon emission computed tomography (SPECT) imaging are elucidated as an alternative method of PSMA image acquisition.
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spelling pubmed-62126182018-11-19 Keeping up with the prostate-specific membrane antigens (PSMAs): an introduction to a new class of positron emission tomography (PET) imaging agents Czarniecki, Marcin Mena, Esther Lindenberg, Liza Cacko, Marek Harmon, Stephanie Radtke, Jan Philipp Giesel, Frederick Turkbey, Baris Choyke, Peter L. Transl Androl Urol Review Article Prostate-specific membrane antigen (PSMA) targeted positron emission tomography (PET) is an emerging prostate cancer imaging method, which has been reported to have a higher sensitivity and specificity than the currently approved PET imaging agents. Multiple PSMA ligands are being investigated around the world and applications range from primary tumor characterization, to local staging, biochemical recurrence, metastasis, and image-guided interventions. The most investigated PET tracers are labelled with 68-Gallium or 18-Fluoride and are discussed in this review. Additionally, (99m)Tc labeled PSMA agents for single photon emission computed tomography (SPECT) imaging are elucidated as an alternative method of PSMA image acquisition. AME Publishing Company 2018-10 /pmc/articles/PMC6212618/ /pubmed/30456186 http://dx.doi.org/10.21037/tau.2018.08.03 Text en 2018 Translational Andrology and Urology. All rights reserved.
spellingShingle Review Article
Czarniecki, Marcin
Mena, Esther
Lindenberg, Liza
Cacko, Marek
Harmon, Stephanie
Radtke, Jan Philipp
Giesel, Frederick
Turkbey, Baris
Choyke, Peter L.
Keeping up with the prostate-specific membrane antigens (PSMAs): an introduction to a new class of positron emission tomography (PET) imaging agents
title Keeping up with the prostate-specific membrane antigens (PSMAs): an introduction to a new class of positron emission tomography (PET) imaging agents
title_full Keeping up with the prostate-specific membrane antigens (PSMAs): an introduction to a new class of positron emission tomography (PET) imaging agents
title_fullStr Keeping up with the prostate-specific membrane antigens (PSMAs): an introduction to a new class of positron emission tomography (PET) imaging agents
title_full_unstemmed Keeping up with the prostate-specific membrane antigens (PSMAs): an introduction to a new class of positron emission tomography (PET) imaging agents
title_short Keeping up with the prostate-specific membrane antigens (PSMAs): an introduction to a new class of positron emission tomography (PET) imaging agents
title_sort keeping up with the prostate-specific membrane antigens (psmas): an introduction to a new class of positron emission tomography (pet) imaging agents
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212618/
https://www.ncbi.nlm.nih.gov/pubmed/30456186
http://dx.doi.org/10.21037/tau.2018.08.03
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