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The dipeptidyl peptidase‐4 (DPP‐4) inhibitor teneligliptin enhances brown adipose tissue function, thereby preventing obesity in mice
To clarify the effects of a dipeptidyl peptidase‐4 (DPP‐4) inhibitor on whole‐body energy metabolism, we treated mice fed a high‐fat diet (HFD) with teneligliptin, a clinically available DPP‐4 inhibitor. Teneligliptin significantly prevented HFD‐induced obesity and obesity‐associated metabolic disor...
Autores principales: | Takeda, Kenichiro, Sawazaki, Honami, Takahashi, Haruya, Yeh, Yu‐Sheng, Jheng, Huei‐Fen, Nomura, Wataru, Ara, Takeshi, Takahashi, Nobuyuki, Seno, Shigeto, Osato, Naoki, Matsuda, Hideo, Kawada, Teruo, Goto, Tsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212644/ https://www.ncbi.nlm.nih.gov/pubmed/30410858 http://dx.doi.org/10.1002/2211-5463.12498 |
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