Cargando…
WNK1 kinase is essential for insulin‐stimulated GLUT4 trafficking in skeletal muscle
With‐no‐lysine 1 (WNK1) kinase is a substrate of the insulin receptor/Akt pathway. Impaired insulin signaling in skeletal muscle disturbs glucose transporter 4 (GLUT4) translocation associated with the onset of type 2 diabetes (T2D). WNK1 is highly expressed in skeletal muscle. However, it is curren...
Autores principales: | Kim, Ji‐Hee, Kim, Hanul, Hwang, Kyu‐Hee, Chang, Jae Seung, Park, Kyu‐Sang, Cha, Seung‐Kuy, Kong, In Deok |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212645/ https://www.ncbi.nlm.nih.gov/pubmed/30410865 http://dx.doi.org/10.1002/2211-5463.12528 |
Ejemplares similares
-
Biological Role of Anti-aging Protein Klotho
por: Kim, Ji-Hee, et al.
Publicado: (2015) -
Insulin-activated store-operated Ca(2+) entry via Orai1 induces podocyte actin remodeling and causes proteinuria
por: Kim, Ji-Hee, et al.
Publicado: (2021) -
Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle
por: Knudsen, Jonas R, et al.
Publicado: (2023) -
Klotho plays a critical role in clear cell renal cell carcinoma progression and clinical outcome
por: Kim, Ji-Hee, et al.
Publicado: (2016) -
Insulin signalling and GLUT4 trafficking in insulin resistance
por: van Gerwen, Julian, et al.
Publicado: (2023)