Precision oncology: separating the wheat from the chaff

Precision oncology based on next-generation sequencing (NGS) test is growing in daily clinical practice. However, the real impact of this strategy in patients’ outcome on a large scale remains uncertain. In this review, we summarise existing literature on this topic, limitations for broad NGS implem...

Descripción completa

Detalles Bibliográficos
Autores principales: Remon, Jordi, Dienstmann, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212683/
https://www.ncbi.nlm.nih.gov/pubmed/30425845
http://dx.doi.org/10.1136/esmoopen-2018-000446
Descripción
Sumario:Precision oncology based on next-generation sequencing (NGS) test is growing in daily clinical practice. However, the real impact of this strategy in patients’ outcome on a large scale remains uncertain. In this review, we summarise existing literature on this topic, limitations for broad NGS implementation, bottlenecks in genomic variant interpretation and the role of molecular tumour boards.

Ejemplares similares