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Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase

Some DNA transposons relocate from one genomic location to another using a mechanism that involves generating double-strand breaks at their transposon ends by forming hairpins on flanking DNA. The same double-strand break mode is employed by the V(D)J recombinase at signal-end/coding-end junctions d...

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Detalles Bibliográficos
Autores principales:	Hickman, Alison B, Voth, Andrea Regier, Ewis, Hosam, Li, Xianghong, Craig, Nancy L, Dyda, Fred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212770/ https://www.ncbi.nlm.nih.gov/pubmed/30239795 http://dx.doi.org/10.1093/nar/gky838

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