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Crystal structure of the modification-dependent SRA-HNH endonuclease TagI

TagI belongs to the recently characterized SRA-HNH family of modification-dependent restriction endonucleases (REases) that also includes ScoA3IV (Sco5333) and TbiR51I (Tbis1). Here, we present a crystal structure of dimeric TagI, which exhibits a DNA binding site formed jointly by the nuclease doma...

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Detalles Bibliográficos
Autores principales: Kisiala, Marlena, Copelas, Alyssa, Czapinska, Honorata, Xu, Shuang-yong, Bochtler, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212794/
https://www.ncbi.nlm.nih.gov/pubmed/30202937
http://dx.doi.org/10.1093/nar/gky781