Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans

Knowing the full set of essential genes for a given organism provides important information about ways to promote, and to limit, its growth and survival. For many non-model organisms, the lack of a stable haploid state and low transformation efficiencies impede the use of conventional approaches to...

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Detalles Bibliográficos
Autores principales: Segal, Ella Shtifman, Gritsenko, Vladimir, Levitan, Anton, Yadav, Bhawna, Dror, Naama, Steenwyk, Jacob L., Silberberg, Yael, Mielich, Kevin, Rokas, Antonis, Gow, Neil A. R., Kunze, Reinhard, Sharan, Roded, Berman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212825/
https://www.ncbi.nlm.nih.gov/pubmed/30377286
http://dx.doi.org/10.1128/mBio.02048-18

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