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Biological and Chemical Diversity of Ascidian-Associated Microorganisms
Ascidians are a class of sessile filter-feeding invertebrates, that provide unique and fertile niches harboring various microorganisms, such as bacteria, actinobacteria, cyanobacteria and fungi. Over 1000 natural products, including alkaloids, cyclic peptides, and polyketides, have been isolated fro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212887/ https://www.ncbi.nlm.nih.gov/pubmed/30275404 http://dx.doi.org/10.3390/md16100362 |
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author | Chen, Lei Hu, Jin-Shuang Xu, Jia-Lei Shao, Chang-Lun Wang, Guang-Yu |
author_facet | Chen, Lei Hu, Jin-Shuang Xu, Jia-Lei Shao, Chang-Lun Wang, Guang-Yu |
author_sort | Chen, Lei |
collection | PubMed |
description | Ascidians are a class of sessile filter-feeding invertebrates, that provide unique and fertile niches harboring various microorganisms, such as bacteria, actinobacteria, cyanobacteria and fungi. Over 1000 natural products, including alkaloids, cyclic peptides, and polyketides, have been isolated from them, which display diverse properties, such as antibacterial, antifungal, antitumor, and anti-inflammatory activities. Strikingly, direct evidence has confirmed that ~8% of natural products from ascidians are actually produced by symbiotic microorganisms. In this review, we present 150 natural products from microorganisms associated with ascidians that have been reported up to 2017. |
format | Online Article Text |
id | pubmed-6212887 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62128872018-11-09 Biological and Chemical Diversity of Ascidian-Associated Microorganisms Chen, Lei Hu, Jin-Shuang Xu, Jia-Lei Shao, Chang-Lun Wang, Guang-Yu Mar Drugs Review Ascidians are a class of sessile filter-feeding invertebrates, that provide unique and fertile niches harboring various microorganisms, such as bacteria, actinobacteria, cyanobacteria and fungi. Over 1000 natural products, including alkaloids, cyclic peptides, and polyketides, have been isolated from them, which display diverse properties, such as antibacterial, antifungal, antitumor, and anti-inflammatory activities. Strikingly, direct evidence has confirmed that ~8% of natural products from ascidians are actually produced by symbiotic microorganisms. In this review, we present 150 natural products from microorganisms associated with ascidians that have been reported up to 2017. MDPI 2018-10-01 /pmc/articles/PMC6212887/ /pubmed/30275404 http://dx.doi.org/10.3390/md16100362 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chen, Lei Hu, Jin-Shuang Xu, Jia-Lei Shao, Chang-Lun Wang, Guang-Yu Biological and Chemical Diversity of Ascidian-Associated Microorganisms |
title | Biological and Chemical Diversity of Ascidian-Associated Microorganisms |
title_full | Biological and Chemical Diversity of Ascidian-Associated Microorganisms |
title_fullStr | Biological and Chemical Diversity of Ascidian-Associated Microorganisms |
title_full_unstemmed | Biological and Chemical Diversity of Ascidian-Associated Microorganisms |
title_short | Biological and Chemical Diversity of Ascidian-Associated Microorganisms |
title_sort | biological and chemical diversity of ascidian-associated microorganisms |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212887/ https://www.ncbi.nlm.nih.gov/pubmed/30275404 http://dx.doi.org/10.3390/md16100362 |
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