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The Risk G Allele of the Single-Nucleotide Polymorphism rs928413 Creates a CREB1-Binding Site That Activates IL33 Promoter in Lung Epithelial Cells
Cytokine interleukin 33 (IL-33) is constitutively expressed by epithelial barrier cells, and promotes the development of humoral immune responses. Along with other proinflammatory mediators released by the epithelium of airways and lungs, it plays an important role in a number of respiratory patholo...
Autores principales: | Gorbacheva, Alisa M., Korneev, Kirill V., Kuprash, Dmitry V., Mitkin, Nikita A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212888/ https://www.ncbi.nlm.nih.gov/pubmed/30257479 http://dx.doi.org/10.3390/ijms19102911 |
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