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The Risk G Allele of the Single-Nucleotide Polymorphism rs928413 Creates a CREB1-Binding Site That Activates IL33 Promoter in Lung Epithelial Cells

Cytokine interleukin 33 (IL-33) is constitutively expressed by epithelial barrier cells, and promotes the development of humoral immune responses. Along with other proinflammatory mediators released by the epithelium of airways and lungs, it plays an important role in a number of respiratory patholo...

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Detalles Bibliográficos
Autores principales: Gorbacheva, Alisa M., Korneev, Kirill V., Kuprash, Dmitry V., Mitkin, Nikita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212888/
https://www.ncbi.nlm.nih.gov/pubmed/30257479
http://dx.doi.org/10.3390/ijms19102911

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