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βTrCP is Required for HIV-1 Vpu Modulation of CD4, GaLV Env, and BST-2/Tetherin

The Human immunodeficiency virus-1 (HIV-1) accessory protein Vpu modulates numerous proteins, including the host proteins CD4 and BST-2/tetherin. Vpu interacts with the Skp, Cullin, F-Box (SCF) ubiquitin ligase through interactions with the F-Box protein βTrCP (1 and/or 2). This interaction is depen...

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Detalles Bibliográficos
Autores principales:	Song, Yul Eum, Cyburt, Daniel, Lucas, Tiffany M., Gregory, Devon A., Lyddon, Terri D., Johnson, Marc C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212966/ https://www.ncbi.nlm.nih.gov/pubmed/30347660 http://dx.doi.org/10.3390/v10100573

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