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Deletion of RasGRF1 Attenuated Interstitial Fibrosis in Streptozotocin-Induced Diabetic Cardiomyopathy in Mice through Affecting Inflammation and Oxidative Stress

Background: Diabetic cardiomyopathy (DCM) is characterized by cardiac fibrosis and stiffness, which often develops into heart failure. This study investigated the role of Ras protein-specific guanine nucleotide releasing factor 1 (RasGRF1) in the development of DCM. Methods: Forty-eight mice were di...

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Detalles Bibliográficos
Autores principales:	Tsai, Tzu-Hsien, Lin, Cheng-Jei, Chua, Sarah, Chung, Sheng-Ying, Chen, Shyh-Ming, Lee, Chien-Ho, Hang, Chi-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213028/ https://www.ncbi.nlm.nih.gov/pubmed/30308936 http://dx.doi.org/10.3390/ijms19103094

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