Effective Sequential Combined Chemotherapy with Trifluridine/Tipiracil and Regorafenib in Human Colorectal Cancer Cells

Salvage chemotherapy for refractory metastatic colorectal cancer using trifluridine/tipiracil (FTD/TPI) and regorafenib has shown survival benefits. We evaluated the antitumor effects of FTD or FTD/TPI combined with regorafenib in vitro and in vivo. SW620, HCT 116, and HT-29 human colorectal cancer...

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Detalles Bibliográficos
Autores principales: Matsuoka, Kazuaki, Nakagawa, Fumio, Tanaka, Nozomu, Okabe, Hiroyuki, Matsuo, Kenichi, Takechi, Teiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213129/
https://www.ncbi.nlm.nih.gov/pubmed/30257515
http://dx.doi.org/10.3390/ijms19102915

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