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(1)H NMR Spectroscopy and MVA to Evaluate the Effects of Caulerpin-Based Diet on Diplodus sargus Lipid Profiles

The biological invasion of the green algae Caulerpa cylindracea represents a serious scientific and public issue in the Mediterranean Sea, essentially due to strong modifications both to habitat structure and native benthic communities. Although alterations in health status and changes in flesh qual...

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Autores principales: Del Coco, Laura, Felline, Serena, Girelli, Chiara Roberta, Angilè, Federica, Magliozzi, Laura, Almada, Frederico, D’Aniello, Biagio, Mollo, Ernesto, Terlizzi, Antonio, Fanizzi, Francesco P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213232/
https://www.ncbi.nlm.nih.gov/pubmed/30340347
http://dx.doi.org/10.3390/md16100390
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author Del Coco, Laura
Felline, Serena
Girelli, Chiara Roberta
Angilè, Federica
Magliozzi, Laura
Almada, Frederico
D’Aniello, Biagio
Mollo, Ernesto
Terlizzi, Antonio
Fanizzi, Francesco P.
author_facet Del Coco, Laura
Felline, Serena
Girelli, Chiara Roberta
Angilè, Federica
Magliozzi, Laura
Almada, Frederico
D’Aniello, Biagio
Mollo, Ernesto
Terlizzi, Antonio
Fanizzi, Francesco P.
author_sort Del Coco, Laura
collection PubMed
description The biological invasion of the green algae Caulerpa cylindracea represents a serious scientific and public issue in the Mediterranean Sea, essentially due to strong modifications both to habitat structure and native benthic communities. Although alterations in health status and changes in flesh quality of some marine species (dietary exposed to C. cylindracea) have been observed, no studies on cause-effect relationships have been carried out. Here, for the first time, through a controlled feeding experiment followed by (1)H NMR Spectroscopy and multivariate analysis (PCA, OPLS-DA), we showed that caulerpin taken with diet is directly responsible of changes observed in metabolic profile of fish flesh, including alteration of lipid metabolism, in particular with a reduction of ω3 PUFA content. The potential of caulerpin to directly modulate lipid metabolism opens up new questions about causal mechanism triggered by algal metabolite also in view of a possible exploitation in the nutraceutical/medical field.
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spelling pubmed-62132322018-11-09 (1)H NMR Spectroscopy and MVA to Evaluate the Effects of Caulerpin-Based Diet on Diplodus sargus Lipid Profiles Del Coco, Laura Felline, Serena Girelli, Chiara Roberta Angilè, Federica Magliozzi, Laura Almada, Frederico D’Aniello, Biagio Mollo, Ernesto Terlizzi, Antonio Fanizzi, Francesco P. Mar Drugs Article The biological invasion of the green algae Caulerpa cylindracea represents a serious scientific and public issue in the Mediterranean Sea, essentially due to strong modifications both to habitat structure and native benthic communities. Although alterations in health status and changes in flesh quality of some marine species (dietary exposed to C. cylindracea) have been observed, no studies on cause-effect relationships have been carried out. Here, for the first time, through a controlled feeding experiment followed by (1)H NMR Spectroscopy and multivariate analysis (PCA, OPLS-DA), we showed that caulerpin taken with diet is directly responsible of changes observed in metabolic profile of fish flesh, including alteration of lipid metabolism, in particular with a reduction of ω3 PUFA content. The potential of caulerpin to directly modulate lipid metabolism opens up new questions about causal mechanism triggered by algal metabolite also in view of a possible exploitation in the nutraceutical/medical field. MDPI 2018-10-18 /pmc/articles/PMC6213232/ /pubmed/30340347 http://dx.doi.org/10.3390/md16100390 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Del Coco, Laura
Felline, Serena
Girelli, Chiara Roberta
Angilè, Federica
Magliozzi, Laura
Almada, Frederico
D’Aniello, Biagio
Mollo, Ernesto
Terlizzi, Antonio
Fanizzi, Francesco P.
(1)H NMR Spectroscopy and MVA to Evaluate the Effects of Caulerpin-Based Diet on Diplodus sargus Lipid Profiles
title (1)H NMR Spectroscopy and MVA to Evaluate the Effects of Caulerpin-Based Diet on Diplodus sargus Lipid Profiles
title_full (1)H NMR Spectroscopy and MVA to Evaluate the Effects of Caulerpin-Based Diet on Diplodus sargus Lipid Profiles
title_fullStr (1)H NMR Spectroscopy and MVA to Evaluate the Effects of Caulerpin-Based Diet on Diplodus sargus Lipid Profiles
title_full_unstemmed (1)H NMR Spectroscopy and MVA to Evaluate the Effects of Caulerpin-Based Diet on Diplodus sargus Lipid Profiles
title_short (1)H NMR Spectroscopy and MVA to Evaluate the Effects of Caulerpin-Based Diet on Diplodus sargus Lipid Profiles
title_sort (1)h nmr spectroscopy and mva to evaluate the effects of caulerpin-based diet on diplodus sargus lipid profiles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213232/
https://www.ncbi.nlm.nih.gov/pubmed/30340347
http://dx.doi.org/10.3390/md16100390
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