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Movement of the RecG Motor Domain upon DNA Binding Is Required for Efficient Fork Reversal

RecG catalyzes reversal of stalled replication forks in response to replication stress in bacteria. The protein contains a fork recognition (“wedge”) domain that binds branched DNA and a superfamily II (SF2) ATPase motor that drives translocation on double-stranded (ds)DNA. The mechanism by which th...

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Detalles Bibliográficos
Autores principales: Warren, Garrett M., Stein, Richard A., Mchaourab, Hassane S., Eichman, Brandt F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213257/
https://www.ncbi.nlm.nih.gov/pubmed/30301235
http://dx.doi.org/10.3390/ijms19103049