Exogenous C(8)-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells

Ceramides, abundant sphingolipids on the cell membrane, can act as signaling molecules to regulate cellular functions including cell viability. Exogenous ceramide has been shown to exert potent anti-proliferative effects against cancer cells, but little is known about how it affects reactive oxygen...

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Detalles Bibliográficos
Autores principales: Chang, Yuli C., Fong, Yao, Tsai, Eing-Mei, Chang, Ya-Gin, Chou, Han Lin, Wu, Chang-Yi, Teng, Yen-Ni, Liu, Ta-Chih, Yuan, Shyng-Shiou, Chiu, Chien-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213533/
https://www.ncbi.nlm.nih.gov/pubmed/30279365
http://dx.doi.org/10.3390/ijms19103010

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